Literature DB >> 1718668

Synthesis and biochemical studies of dithioate DNA.

M H Caruthers1, G Beaton, L Cummins, D Graff, Y X Ma, W S Marshall, H Sasmor, P Norris, E K Yau.   

Abstract

Dithioate DNA was synthesized and used for various biochemical studies. Results from these studies indicate that dithioate DNA is a potent inhibitor of HIV Reverse Transcriptase, activates endogenous RNase H in HeLa cell nuclear extracts, and is a useful probe for studying protein-DNA interactions.

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Year:  1991        PMID: 1718668     DOI: 10.1002/9780470514085.ch11

Source DB:  PubMed          Journal:  Ciba Found Symp        ISSN: 0300-5208


  1 in total

1.  Solid phase synthesis of oligodeoxyribonucleoside phosphorodithioates from thiophosphoramidites.

Authors:  K Bjergårde; O Dahl
Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971

  1 in total

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