Literature DB >> 17186395

Misuse of antithrombotic therapy in atrial fibrillation patients: frequent, pervasive and persistent.

Luciana S Fornari1, Daniela Calderaro, Ivana B Nassar, Cristiane Lauretti, Lidia Nakamura, Renato Bagnatori, Walter Ageno, Bruno Caramelli.   

Abstract

PURPOSE: To assess the use of antithrombotic therapy among atrial fibrillation (AF) patients in a Brazilian University Heart Hospital (InCor). METHODS AND
RESULTS: In a cross-sectional study we analyzed the charts of all patients treated at InCor in five separate days of 2002 (Phase 1). To assess the impact of admission to a cardiology hospital, a follow-up of the AF patients selected in Phase 1 was carried out after 1 year (Phase 2). The prevalence of AF in the 3,764 assessed charts was 8.0% (301 patients). In Phase 1, antiplatelets were prescribed to 21.2% and anticoagulant therapy (ACT) to 46.5% of AF patients; in Phase 2, to 19.9 and 57.8%, respectively. Thus, 32.2% (Phase 1) and 22.2% (Phase 2) of AF patients were not receiving any antithrombotic drug. Among AF patients with previous ischemic stroke (17.6%), only 49% (Phase 1) and 60.4% (Phase 2) were receiving ACT. As many as 34 and 22.6%, respectively, were not receiving any antithrombotic drug. After follow-up, a new acute embolic event was documented in 5.6% of patients, 17% died.
CONCLUSIONS: Anticoagulation is underused in AF patients and neither the fact of being treated by cardiologists in a University Hospital, nor the learning time-window of 1 year seemed to improve the antithrombotic care significantly.

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Year:  2007        PMID: 17186395     DOI: 10.1007/s11239-006-9012-9

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  44 in total

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Review 4.  Atrial fibrillation: the current epidemic.

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Review 5.  Stroke Prevention in Atrial Fibrillation: Focus on Latin America.

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Journal:  Arq Bras Cardiol       Date:  2016-08-11       Impact factor: 2.000

6.  Which Method to Use for Surgical Ablation of Atrial Fibrillation Performed Concomitantly with Mitral Valve Surgery: Radiofrequency Ablation versus Cryoablation.

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7.  Factors in Deciding between Novel and Traditional Oral Anticoagulants to Prevent Embolism in Atrial Fibrillation Patients.

Authors:  Maurício Scanavacca; Francisco Darrieux
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Review 8.  Use of Guidelines for Reducing Stroke Risk in Patients With Nonvalvular Atrial Fibrillation: A Review From a Latin American Perspective.

Authors:  Carlos Cantú-Brito; Gisele Sampaio Silva; Sebastián F Ameriso
Journal:  Clin Appl Thromb Hemost       Date:  2017-10-09       Impact factor: 2.389

  8 in total

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