Literature DB >> 17185826

Small leucine-rich proteoglycans in the aging skeleton.

M F Young1, Y Bi, L Ameye, T Xu, S Wadhwa, A Heegaard, T Kilts, X D Chen.   

Abstract

Small Leucine-Rich Proteoglyans (SLRPs) are major skeletal extracellular matrix (ECM) components that comprise a family of 13 members containing repeats of a leucine-rich motif. To examine SLRP function, we generated mice deficient in one or more member and analyzed them at the tissue, cell and molecular levels. This review outlines the novel research findings uncovered using these new animal models.

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Year:  2006        PMID: 17185826

Source DB:  PubMed          Journal:  J Musculoskelet Neuronal Interact        ISSN: 1108-7161            Impact factor:   2.041


  10 in total

Review 1.  Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.

Authors:  Kristin Moreth; Renato V Iozzo; Liliana Schaefer
Journal:  Cell Cycle       Date:  2012-06-01       Impact factor: 4.534

2.  Potential role of cathepsin K in the pathophysiology of mucopolysaccharidoses.

Authors:  Susan Wilson; Dieter Brömme
Journal:  J Pediatr Rehabil Med       Date:  2010

Review 3.  Biglycan in the Skeleton.

Authors:  Vardit Kram; Reut Shainer; Priyam Jani; Josephina A N Meester; Bart Loeys; Marian F Young
Journal:  J Histochem Cytochem       Date:  2020-07-06       Impact factor: 2.479

4.  Extracellular Matrix Mediates BMP-2 in a Model of Temporomandibular Joint Osteoarthritis.

Authors:  Maya Shirakura; Vardit Kram; Jennifer Robinson; Sheena Sikka; Tina M Kilts; Sunil Wadhwa; Marian F Young
Journal:  Cells Tissues Organs       Date:  2017-04-19       Impact factor: 2.481

5.  Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix.

Authors:  Rui Hua; Qingwen Ni; Travis D Eliason; Yan Han; Sumin Gu; Daniel P Nicolella; Xiaodu Wang; Jean X Jiang
Journal:  Matrix Biol       Date:  2020-09-28       Impact factor: 11.583

6.  Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity.

Authors:  Jin-Young Lee; Da-Ae Kim; Eun-Young Kim; Eun-Ju Chang; So-Jeong Park; Beom-Jun Kim
Journal:  Int J Mol Sci       Date:  2021-04-29       Impact factor: 5.923

Review 7.  Biglycan: a multivalent proteoglycan providing structure and signals.

Authors:  Madalina V Nastase; Marian F Young; Liliana Schaefer
Journal:  J Histochem Cytochem       Date:  2012-07-20       Impact factor: 2.479

Review 8.  Small leucine-rich proteoglycans in physiological and biomechanical function of bone.

Authors:  Rui Hua; Jean X Jiang
Journal:  Matrix Biol Plus       Date:  2021-05-06

9.  Small leucine rich proteoglycans, a novel link to osteoclastogenesis.

Authors:  Vardit Kram; Tina M Kilts; Nisan Bhattacharyya; Li Li; Marian F Young
Journal:  Sci Rep       Date:  2017-10-03       Impact factor: 4.379

10.  AGE-RELATED DETERIORATION OF BONE TOUGHNESS IS RELATED TO DIMINISHING AMOUNT OF MATRIX GLYCOSAMINOGLYCANS (GAGS).

Authors:  Xiaodu Wang; Rui Hua; Abu Ahsan; Qingwen Ni; Yehong Huang; Sumin Gu; Jean X Jiang
Journal:  JBMR Plus       Date:  2017-12-28
  10 in total

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