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Literature DB >> 17185433

Antenatal risk factors, cytokines and the development of atopic disease in early childhood.

E K Chung¹, R L Miller, M T Wilson, S J McGeady, J F Culhane.

Abstract

Atopic diseases are complex entities influenced by an array of risk factors, including genetic predisposition, environmental allergens, antenatal exposures, infections and psychosocial factors. One proposed mechanism by which these risk factors contribute to the development of atopic disease is through changes in the production of T helper cell type 1 (Th1) and T helper cell type 2 (Th2) cytokines. The objectives of this review are to discuss antenatal exposures that are associated with paediatric atopic diseases, to discuss the influence of the intrauterine environment on neonatal immune responses, to provide an overview of the Th1 and Th2 pathways and how they relate to atopic disease, and to summarise our current understanding of the association between cytokine responses in cord blood and the development of atopic disease in early childhood.

Entities: Disease Gene

Mesh：

Substances：
Cytokines
Epitopes

Year: 2007 PMID： 17185433 PMCID： PMC2675311 DOI： 10.1136/adc.2006.106492

Source DB: PubMed Journal: Arch Dis Child Fetal Neonatal Ed ISSN： 1359-2998 Impact factor: 5.747

67 in total

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Journal: Am J Respir Crit Care Med Date: 1999-07 Impact factor: 21.405

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Journal: J Allergy Clin Immunol Date: 2005-09 Impact factor: 10.793

4. Antibiotic exposure in early infancy and risk for childhood atopy.

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Journal: J Allergy Clin Immunol Date: 2005-06 Impact factor: 10.793

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Journal: Clin Exp Allergy Date: 1999-05 Impact factor: 5.018

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Authors: C H Hughes; R C Jones; D E Wright; F F Dobbs
Journal: Clin Exp Allergy Date: 1999-10 Impact factor: 5.018

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Journal: Int J Epidemiol Date: 1999-08 Impact factor: 7.196

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Journal: Clin Exp Allergy Date: 1998-11 Impact factor: 5.018

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Journal: Lancet Date: 1999-01-16 Impact factor: 79.321

11 in total

1. Prenatal maternal diet affects asthma risk in offspring.

Authors: Rachel L Miller
Journal: J Clin Invest Date: 2008-10 Impact factor: 14.808

2. Cytokine expression in cord blood cells of children of healthy and allergic mothers.

Authors: J Hrdý; P Zanvit; O Novotná; I Kocourková; J Zižka; L Prokešová
Journal: Folia Microbiol (Praha) Date: 2010-10-13 Impact factor: 2.099

3. Parental characteristics, somatic fetal growth, and season of birth influence innate and adaptive cord blood cytokine responses.

Authors: Diane R Gold; Gordon R Bloomberg; William W Cruikshank; Cynthia M Visness; John Schwarz; Meyer Kattan; George T O'Connor; Robert A Wood; Melissa S Burger; Rosalind J Wright; Frank Witter; Aviva Lee-Parritz; Rhoda Sperling; Yoel Sadovsky; Alkis Togias; James E Gern
Journal: J Allergy Clin Immunol Date: 2009-11 Impact factor: 10.793

4. Impaired function of regulatory T cells in cord blood of children of allergic mothers.

Authors: J Hrdý; I Kocourková; L Prokešová
Journal: Clin Exp Immunol Date: 2012-10 Impact factor: 4.330

5. Neonatal bilirubin levels and childhood asthma in the US Collaborative Perinatal Project, 1959-1965.

Authors: Lisu Huang; Yixiao Bao; Zongli Xu; Xiaoping Lei; Yan Chen; Yongjun Zhang; Jun Zhang
Journal: Am J Epidemiol Date: 2013-10-31 Impact factor: 4.897

6. Histological chorioamnionitis is associated with an increased risk of wheezing in preterm children less than 34 gestational weeks.

Authors: Xiaoli Wang; Haiyuan Li; Qianqian Zhang; Qianwen Shen; Dan Zhu; Hong Li; Zheng Tang; Jiuru Zhao; Zhiwei Liu
Journal: BMC Pediatr Date: 2021-03-01 Impact factor: 2.125

7. Cord blood cellular proliferative response as a predictive factor for atopic dermatitis at 12 months.

Authors: Hyo-Bin Kim; Kang Mo Ahn; Kyung Won Kim; Youn Ho Shin; Jinho Yu; Ju-Hee Seo; Hyung Young Kim; Ji-Won Kwon; Byoung-Ju Kim; Ja-Young Kwon; Suk-Joo Choi; Kyung-Ju Lee; Hee Jin Park; Hye-Sung Won; Soo-Jong Hong
Journal: J Korean Med Sci Date: 2012-10-30 Impact factor: 2.153