Literature DB >> 1718471

Fluorescence, CD, and NMR studies on spantide, a bombesin and substance P antagonist.

C Di Bello1, A Scatturin, G D'Auria, M Gargiulo, L Paolillo, E Trivellone, R De Castiglione.   

Abstract

The conformational properties of spantide [(D-Arg, D-Trp, Leu) substance P] have been studied by fluorescence, CD, and nmr techniques. The fluorescence, CD, and nmr parameters in different solvents and in a micellar environment (SDS) are compared with the data collected for bombesin. A preliminary investigation on [D-Pro] spantide is also reported.

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Year:  1991        PMID: 1718471     DOI: 10.1002/bip.360310609

Source DB:  PubMed          Journal:  Biopolymers        ISSN: 0006-3525            Impact factor:   2.505


  1 in total

1.  The lipid-associated 3D structure of SPA, a broad-spectrum neuropeptide antagonist with anticancer properties.

Authors:  David A Keire; Mohanraja Kumar; Weidong Hu; James Sinnett-Smith; Enrique Rozengurt
Journal:  Biophys J       Date:  2006-09-22       Impact factor: 4.033

  1 in total

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