Literature DB >> 17183363

The chromatoid body: a germ-cell-specific RNA-processing centre.

Noora Kotaja1, Paolo Sassone-Corsi.   

Abstract

The chromatoid body, a unique cloud-like structure of male germ cells, moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades. Recent findings indicate that microRNA and RNA-decay pathways converge to the chromatoid body. This highly specialized structure might function as an intracellular focal domain that organizes and controls RNA processing in male germ cells.

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Year:  2007        PMID: 17183363     DOI: 10.1038/nrm2081

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  112 in total

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6.  Relevance of gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) in the structural integrity of the chromatoid body during spermatogenesis.

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7.  A novel requirement in mammalian spermatid differentiation for the DAZ-family protein Boule.

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8.  Cloning and expression profiling of testis-expressed microRNAs.

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9.  Integrative proteomic and transcriptomic analyses reveal multiple post-transcriptional regulatory mechanisms of mouse spermatogenesis.

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Review 10.  Effects of stress and aging on ribonucleoprotein assembly and function in the germ line.

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Journal:  Wiley Interdiscip Rev RNA       Date:  2013-11-13       Impact factor: 9.957

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