Literature DB >> 17181057

Evaluation of the progeny of rats treated with topoisomerase II inhibitor vepesid.

T G Borovskaya1, V E Gol'dberg, Yu A Shchemerova, A V Perova, E A Timina, A V Pakhomova.   

Abstract

Progeny of Wistar rats treated with vepesid 1, 3, and 6 months before mating is characterized by common pathological changes. These changes were more pronounced and more diverse in animals descending from females receiving the cytostatic compared to the progeny of treated males. The severity of toxic effects depended on the period between mating and vepesid treatment. Cytostatic treatment 3 months before mating was associated with minimum toxicity for the progeny.

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Year:  2006        PMID: 17181057     DOI: 10.1007/s10517-006-0225-x

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

1.  Investigation of the anticancer and apoptotic effect of Micromeria congesta under in vitro conditions and detection of related genes by real-time PCR.

Authors:  Hikmet Dinç; Akın Yiğin; İsmail Koyuncu; Mustafa Aslan
Journal:  Vet Res Forum       Date:  2022-03-15       Impact factor: 0.950

  1 in total

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