Nazimul Hussain1, Taraprasad Das2, Rohit Khanna3, Kallukuri Sumasri2, Lakshmana Samudram Mohan Ram2. 1. Smt. Kanuri Santhamma Retina Vitreous Centre, Hyderabad, Andhra Pradesh, India. nazimul@lvpei.org. 2. Smt. Kanuri Santhamma Retina Vitreous Centre, Hyderabad, Andhra Pradesh, India. 3. ICARE, L.V. Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.
Abstract
PURPOSE: To determine visual outcome after a 12-month follow-up period of verteporfin therapy for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Indian patients. METHODS: Twenty-five patients (26 eyes) who completed a 12-month follow-up after photodynamic therapy for subfoveal CNV secondary to AMD were included in the study. The follow-up schedule was every month for 2 months and then every 3 months thereafter until 12 months. Improvement in visual acuity was defined as a >or=10-letter gain, and deterioration as a >or=10-letter loss in the Early Treatment Diabetic Retinopathy Study chart at 4 m. RESULTS: The mean age of the 25 patients was 62.3 +/- 9 years. There were 17 male patients (68%). The mean initial letter acuity was 28. 4 +/- 14.1, and the final letter acuity was 25.5 +/- 18.4 at 12 months. Initial visual acuity was >or=20/40 in seven eyes, 20/50-20/80 in nine eyes, and 20/100-20/200 in ten eyes; seven eyes had a >or=10-letter gain, and three eyes had a >or=10-letter loss. At the end of 12 months, six eyes had a >or=10-letter gain and ten eyes had a >or=10-letter loss. CONCLUSION: Photodynamic therapy appears to preserve the vision in subfoveal CNV secondary to AMD in the eyes of Indian patients.
PURPOSE: To determine visual outcome after a 12-month follow-up period of verteporfin therapy for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Indian patients. METHODS: Twenty-five patients (26 eyes) who completed a 12-month follow-up after photodynamic therapy for subfoveal CNV secondary to AMD were included in the study. The follow-up schedule was every month for 2 months and then every 3 months thereafter until 12 months. Improvement in visual acuity was defined as a >or=10-letter gain, and deterioration as a >or=10-letter loss in the Early Treatment Diabetic Retinopathy Study chart at 4 m. RESULTS: The mean age of the 25 patients was 62.3 +/- 9 years. There were 17 male patients (68%). The mean initial letter acuity was 28. 4 +/- 14.1, and the final letter acuity was 25.5 +/- 18.4 at 12 months. Initial visual acuity was >or=20/40 in seven eyes, 20/50-20/80 in nine eyes, and 20/100-20/200 in ten eyes; seven eyes had a >or=10-letter gain, and three eyes had a >or=10-letter loss. At the end of 12 months, six eyes had a >or=10-letter gain and ten eyes had a >or=10-letter loss. CONCLUSION: Photodynamic therapy appears to preserve the vision in subfoveal CNV secondary to AMD in the eyes of Indian patients.
Authors: Neil M Bressler; Jennifer Arnold; Mustapha Benchaboune; Mark S Blumenkranz; Gary E Fish; Evangelos S Gragoudas; Hilel Lewis; Ursula Schmidt-Erfurth; Jason S Slakter; Susan B Bressler; Kelly Manos; Yong Hao; Laurie Hayes; John Koester; Al Reaves; H Andrew Strong Journal: Arch Ophthalmol Date: 2002-11
Authors: Mohammad Azab; David S Boyer; Neil M Bressler; Susan B Bressler; Ilona Cihelkova; Young Hao; Ilkka Immonen; Jennifer I Lim; Ugo Menchini; Joel Naor; Michael J Potter; Al Reaves; Philip J Rosenfeld; Jason S Slakter; Peter Soucek; H Andrew Strong; Andrea Wenkstern; Xiang Yao Su; Yit C Yang Journal: Arch Ophthalmol Date: 2005-04