Literature DB >> 17180237

A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.

Felix Freire1, Igor Cuesta, Francisco Corzana, Julia Revuelta, Carlos González, Milos Hricovini, Agatha Bastida, Jesús Jiménez-Barbero, Juan Luis Asensio.   

Abstract

A complete characterisation of the protonation equilibrium that accompanies the molecular recognition of neomycin-B by a specific RNA receptor has been achieved by employing simple NMR measurements.

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Year:  2006        PMID： 17180237     DOI： 10.1039/b611597g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Molecular mechanisms for dynamic regulation of N1 riboswitch by aminoglycosides.

Authors:  Marta Kulik; Takaharu Mori; Yuji Sugita; Joanna Trylska
Journal:  Nucleic Acids Res       Date:  2018-11-02       Impact factor: 16.971

2.  Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality.

Authors:  Christopher M Barbieri; Malvika Kaul; Melanie Bozza-Hingos; Fang Zhao; Yitzhak Tor; Thomas Hermann; Daniel S Pilch
Journal:  Antimicrob Agents Chemother       Date:  2007-03-12       Impact factor: 5.191

3.  Effects of guanidino modified aminoglycosides on mammalian membranes studied using a quartz crystal microbalance.

Authors:  Torsten John; Zhi Xiang Voo; Clemens Kubeil; Bernd Abel; Bim Graham; Leone Spiccia; Lisandra L Martin
Journal:  Medchemcomm       Date:  2017-04-06       Impact factor: 3.597

4.  A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates.

Authors:  Beata Mrugała; Anna Miłaczewska; Przemyslaw Jerzy Porebski; Ewa Niedzialkowska; Maciej Guzik; Wladek Minor; Tomasz Borowski
Journal:  FEBS J       Date:  2020-07-27       Impact factor: 5.542

5.  Charge reduction and thermodynamic stabilization of substrate RNAs inhibit RNA editing.

Authors:  W-Matthias Leeder; Andreas J Reuss; Michael Brecht; Katja Kratz; Josef Wachtveitl; H Ulrich Göringer
Journal:  PLoS One       Date:  2015-03-05       Impact factor: 3.240

6.  Building a stable RNA U-turn with a protonated cytidine.

Authors:  Sina R Gottstein-Schmidtke; Elke Duchardt-Ferner; Florian Groher; Julia E Weigand; Daniel Gottstein; Beatrix Suess; Jens Wöhnert
Journal:  RNA       Date:  2014-06-20       Impact factor: 4.942

7.  Multinuclear Nuclear Magnetic Resonance Spectroscopy Is Used to Determine Rapidly and Accurately the Individual pK a Values of 2-Deoxystreptamine, Neamine, Neomycin, Paromomycin, and Streptomycin.

Authors:  Abdulaziz H Alkhzem; Timothy J Woodman; Ian S Blagbrough
Journal:  ACS Omega       Date:  2021-01-20

8.  Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

Authors:  Dale W Hailey; Brock Roberts; Kelly N Owens; Andrew K Stewart; Tor Linbo; Remy Pujol; Seth L Alper; Edwin W Rubel; David W Raible
Journal:  PLoS Genet       Date:  2012-10-11       Impact factor: 5.917
  8 in total

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