OBJECTIVE: We examined age associated variation in salivary testosterone values among Japanese males as well as anthropometric measurements. METHODS: Salivary samples were collected in pretreated sodium azide treated tubes. The first series: 15-79-year-old males (n = 99); two morning and two evening samples were collected at home for two days. The second series: 90-year-old males (n = 29); one morning sample was collected. Testosterone values were determined using an iodine125-based radioimmunoassay kit modified for saliva. RESULTS: Results show 1) a significant decrease in salivary testosterone values from 20s to 40s and older, 2) no significant decline after 40 through 90 years old, 3) no significant age-related differences in the degree of intraindividual diurnal fluctuation across age groups of 40-70s, and 4) higher BMI is associated with the lower salivary testosterone among 40-70s. CONCLUSIONS: These results suggest that neither a constant decrease of salivary testosterone values or markedly reduced intraindividual fluctations are universal aspects of aging. Older males may maintain relatively high testosterone levels compared to younger men and a relatively 'robust' neuroendocrinological system.
OBJECTIVE: We examined age associated variation in salivary testosterone values among Japanese males as well as anthropometric measurements. METHODS: Salivary samples were collected in pretreated sodium azide treated tubes. The first series: 15-79-year-old males (n = 99); two morning and two evening samples were collected at home for two days. The second series: 90-year-old males (n = 29); one morning sample was collected. Testosterone values were determined using an iodine125-based radioimmunoassay kit modified for saliva. RESULTS: Results show 1) a significant decrease in salivary testosterone values from 20s to 40s and older, 2) no significant decline after 40 through 90 years old, 3) no significant age-related differences in the degree of intraindividual diurnal fluctuation across age groups of 40-70s, and 4) higher BMI is associated with the lower salivary testosterone among 40-70s. CONCLUSIONS: These results suggest that neither a constant decrease of salivary testosterone values or markedly reduced intraindividual fluctations are universal aspects of aging. Older males may maintain relatively high testosterone levels compared to younger men and a relatively 'robust' neuroendocrinological system.
Authors: Asher Y Rosinger; Herman Pontzer; David A Raichlen; Brian M Wood; Susan N Tanner; Jeff M Sands Journal: Am J Phys Anthropol Date: 2019-01-31 Impact factor: 2.868
Authors: Stephen B Manuck; Anna L Marsland; Janine D Flory; Adam Gorka; Robert E Ferrell; Ahmad R Hariri Journal: Psychoneuroendocrinology Date: 2010-01 Impact factor: 4.905
Authors: Benjamin C Trumble; Daniel K Cummings; Kathleen A O'Connor; Darryl J Holman; Eric A Smith; Hillard S Kaplan; Michael D Gurven Journal: Evol Hum Behav Date: 2013-09-01 Impact factor: 4.178