Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Pregabalin for pain management.

Literature DB >> 17177755

Pregabalin for pain management.

Abstract

Pregabalin is a new analog of the neurotransmitter gamma-aminobutyric acid (GABA). It is an alpha2-delta (alpha2-delta) ligand that has analgesic, anticonvulsant, and anxiolytic activity. Alpha2-delta is an auxiliary protein associated with voltage-gated calcium channels. Pregabalin binds potently to the alpha2-delta subunit resulting in modulation of calcium channels and reduction in the release of several neurotransmitters, including glutamate, norepinephrine, serotonin, dopamine, and substance P. This review discusses the pharmacology of this medication as well as available studies in patients.

Entities: Chemical Disease Gene Species

Year: 2005 PMID： 17177755 DOI： 10.1111/j.1533-2500.2005.05205.x

Source DB: PubMed Journal: Pain Pract ISSN： 1530-7085 Impact factor: 3.183

Keyword Cloud
Cited

13 in total

1. Pregabalin- and topiramate-mediated regulation of cognitive and motor impulsivity in DBA/2 mice.

Authors: Francisco Navarrete; José M Pérez-Ortiz; Jorge Manzanares
Journal: Br J Pharmacol Date: 2012-09 Impact factor: 8.739

Review 2. The determination and application of fixed-dose analgesic combinations for treating multimodal pain.

Authors: Robert B Raffa; Joseph V Pergolizzi; Ronald J Tallarida
Journal: J Pain Date: 2010-03-24 Impact factor: 5.820

3. Effectiveness of preanesthetic administration of gabapentin on sedative action during intravenous sedation with propofol.

Authors: Rumiko Hosokawa; Shinichi Ito; Jun Hirokawa; Yu Oshima; Takeshi Yokoyama
Journal: J Anesth Date: 2018-09-20 Impact factor: 2.078

4. Sedative effects of oral pregabalin premedication on intravenous sedation using propofol target-controlled infusion.

Authors: Noriko Karube; Shinichi Ito; Saori Sako; Jun Hirokawa; Takeshi Yokoyama
Journal: J Anesth Date: 2017-05-02 Impact factor: 2.078

5. The effects of co-administration of pregabalin and vitamin E on neuropathic pain induced by partial sciatic nerve ligation in male rats.

Authors: Manzumeh-Shamsi Meymandi; Gholamreza Sepehri; Mona Abdolsamadi; Mohammad Shaabani; Gioia Heravi; Omid Yazdanpanah; Mohammadmehdi-Moeini Aghtaei
Journal: Inflammopharmacology Date: 2017-02-23 Impact factor: 4.473

10. The effect of pregabalin and duloxetine treatment on quality of life of breast cancer patients with taxane-induced sensory neuropathy: A randomized clinical trial.

Authors: Razieh Avan; Ghasem Janbabaei; Narjes Hendouei; Abbas Alipour; Samaneh Borhani; Nasim Tabrizi; Ebrahim Salehifar
Journal: J Res Med Sci Date: 2018-06-06 Impact factor: 1.852

Pregabalin for pain management.

1. Pregabalin- and topiramate-mediated regulation of cognitive and motor impulsivity in DBA/2 mice.

Review 2. The determination and application of fixed-dose analgesic combinations for treating multimodal pain.

3. Effectiveness of preanesthetic administration of gabapentin on sedative action during intravenous sedation with propofol.

4. Sedative effects of oral pregabalin premedication on intravenous sedation using propofol target-controlled infusion.

5. The effects of co-administration of pregabalin and vitamin E on neuropathic pain induced by partial sciatic nerve ligation in male rats.

Review 6. Neuromodulators for the treatment of headache disorders and fibromyalgia.

7. Gabapentin for decerebrate rigidity: a case report.

8. Pregabalin Did Not Improve Pain Management After Spinal Fusions.

9. Pregabalin-induced self-harm behavior.

10. The effect of pregabalin and duloxetine treatment on quality of life of breast cancer patients with taxane-induced sensory neuropathy: A randomized clinical trial.