| Literature DB >> 17177074 |
Abstract
The myelin sheath is an insulating membrane layer surrounding myelinated axons in vertebrates, which is formed when the plasma membrane of an oligodendrocyte or a Schwann cell wraps itself around the axon. A large fraction of the total protein in this membrane layer is comprised of only a small number of individual proteins, which have certain intriguing structural properties. The myelin proteins are implicated in a number of neurological diseases, including, for example, autoimmune diseases and peripheral neuropathies. In this review, the structural properties of a number of myelin-specific proteins are described.Entities:
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Year: 2006 PMID: 17177074 DOI: 10.1007/s00726-006-0479-7
Source DB: PubMed Journal: Amino Acids ISSN: 0939-4451 Impact factor: 3.520