OBJECTIVE: To study the impact of co-existing psychiatric problems with ADHD on behavioural features, psychosocial functioning and quality of life in subjects of the ADORE cohort (N=1,478). METHODS: The following six groups of associated psychiatric problems with ADHD were compared: oppositional-defiant disorder or conduct disorder only (ODD/CD); anxiety or depressive disorder only (ANX/DEP); tic/Tourette's disorder only (TIC/Tourette's); developmental co-ordination disorder only (DCD); two or more associated conditions; and none. Dependent variables included the ADHD Rating Scale-IV, the Strengths and Difficulties Questionnaire, the Clinical Global Impression-Severity scale, the Children's Global Assessment Scale and the Child Health Illness Profile-Child Edition. RESULTS: Having multiple co-existing psychiatric problems increased the severity of ADHD in all domains, be it behavioural features, psychosocial impairment or deterioration of quality of life. A similar though less consistent pattern applied to subjects with co-existing ODD/CD. CONCLUSIONS: The ADORE study provides impressive evidence for the far-reaching consequences of co-existing psychiatric problems in children with ADHD that warrant intensive consideration in clinical assessment and treatment.
OBJECTIVE: To study the impact of co-existing psychiatric problems with ADHD on behavioural features, psychosocial functioning and quality of life in subjects of the ADORE cohort (N=1,478). METHODS: The following six groups of associated psychiatric problems with ADHD were compared: oppositional-defiant disorder or conduct disorder only (ODD/CD); anxiety or depressive disorder only (ANX/DEP); tic/Tourette's disorder only (TIC/Tourette's); developmental co-ordination disorder only (DCD); two or more associated conditions; and none. Dependent variables included the ADHD Rating Scale-IV, the Strengths and Difficulties Questionnaire, the Clinical Global Impression-Severity scale, the Children's Global Assessment Scale and the Child Health Illness Profile-Child Edition. RESULTS: Having multiple co-existing psychiatric problems increased the severity of ADHD in all domains, be it behavioural features, psychosocial impairment or deterioration of quality of life. A similar though less consistent pattern applied to subjects with co-existing ODD/CD. CONCLUSIONS: The ADORE study provides impressive evidence for the far-reaching consequences of co-existing psychiatric problems in children with ADHD that warrant intensive consideration in clinical assessment and treatment.
Authors: A Karmakar; S Maitra; D Verma; B Chakraborti; R Goswami; P Ghosh; S Sinha; K P Mohanakumar; R Usha; K Mukhopadhyay Journal: Neurochem Res Date: 2014-03-21 Impact factor: 3.996
Authors: Peter M Wehmeier; Alexander Schacht; Ralf W Dittmann; Karin Helsberg; Christian Schneider-Fresenius; Martin Lehmann; Monika Bullinger; Ulrike Ravens-Sieberer Journal: Qual Life Res Date: 2010-12-07 Impact factor: 4.147
Authors: Kwame A Nyarko; Scott D Grosse; Melissa L Danielson; Joseph R Holbrook; Susanna N Visser; Stuart K Shapira Journal: J Child Adolesc Psychopharmacol Date: 2017-03-22 Impact factor: 2.576
Authors: R C Kessler; L A Adler; P Berglund; J G Green; K A McLaughlin; J Fayyad; L J Russo; N A Sampson; V Shahly; A M Zaslavsky Journal: Psychol Med Date: 2013-10-08 Impact factor: 7.723