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Literature DB >> 17176633

Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Chung K Chu¹, Srinivas Gadthula, Xin Chen, Hyunah Choo, Sureyya Olgen, Dale L Barnard, Robert W Sidwell.

Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2006 PMID： 17176633 DOI： 10.1177/095632020601700506

Source DB: PubMed Journal: Antivir Chem Chemother ISSN： 0956-3202

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Cited

15 in total

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Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-coV).

Review 1. The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.

2. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

3. Identification of potential SARS-CoV-2 inhibitors from South African medicinal plant extracts using molecular modelling approaches.

Review 4. Essential functional molecules associated with SARS-CoV-2 infection: Potential therapeutic targets for COVID-19.

Review 5. Potential compounds from several Indonesian plants to prevent SARS-CoV-2 infection: A mini-review of SARS-CoV-2 therapeutic targets.

Review 6. Molecular targets for COVID-19 drug development: Enlightening Nigerians about the pandemic and future treatment.

Review 7. Coronavirus Pandemic-Therapy and Vaccines.

Review 8. SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets.

9. Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods.

Review 10. Structural and functional insights into non-structural proteins of coronaviruses.