Clear differences in hand-held dermoscopes.

In order to correctly evaluate melanocytic and non-melanocytic skin tumors using a hand-held dermoscope, it is essential to have adequate magnification and illumination to allow the differential structures to be clearly seen. One example of a dysplastic compound melanocytic nevus and a thin malignant melanoma were examined with five different handheld dermoscopes (Heine Delta 10, Heine Delta 20, Dermogenius and Dermlite Foto 37 with and without glass plate) in order to assess the image quality. The magnification was identical in all dermoscopes. In the newer dermoscopes (Heine Delta 20, Dermogenius and Dermlite Foto 37 with and without glass plate) the light sources were clearly improved, as now 6 or 24 LEDs, respectively, are employed. This distinctly improved the image quality with regard to color and visible differential structures compared to the dermoscope (Heine Delta 10) with only one light source. Clear differences is assessing differential structures were seen in one dermoscope (Dermlite Foto 37 without glass plate). Using this dermoscope without any glass plate or liquid between the dermoscope and the skin, exophytic tumors were better visualized in a three-dimensional fashion but fewer differential structures were seen.