| Literature DB >> 17175822 |
Nikolaos Dabarakis1, Anastasios Tsirlis, Nikolaos Parisis, Dimitrios Tsoukalas.
Abstract
The role of temperature in the action of local anesthetics was studied in 20 healthy young volunteers with plain 3% mepivacaine injected periapically twice in their maxillary first premolar, the first time with the solution at a temperature of 20 degrees C and the second time at 4 degrees C. The pulpal response was measured with a pulp tester every minute. The onset of pulp anesthesia was found to be of no statistical difference between 20 degrees C and 4 degrees C. On the other hand, mepivacaine at a temperature of 4 degrees C was found to have a statistically significant longer duration of action. Our conclusion is that the drop in temperature of mepivacaine from 20 degrees C to 4 degrees C provides a longer duration of pulpal anesthesia.Entities:
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Year: 2006 PMID： 17175822 PMCID： PMC1693662 DOI： 10.2344/0003-3006(2006)53[91:TROTIT]2.0.CO;2
Source DB: PubMed Journal: Anesth Prog ISSN： 0003-3006