| Literature DB >> 17175384 |
Adrian Tempescul1, Gaëlle Guillerm, Nathalie Douet-Guilbert, Frédéric Morel, Marie-Josée Le Bris, Marc De Braekeleer.
Abstract
We report here two cases of patients with acute myeloblastic leukemia, type M1 (FAB classification), associated with a t(10;17)(p15;q21). Fluorescence in situ hybridization with the LSI PML/RARA dual-color probe showed the breakpoint to be distal to the RARA locus. Four other patients with this translocation have been reported, three of them having acute undifferentiated or poorly differentiated leukemia.Entities:
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Year: 2007 PMID： 17175384 DOI： 10.1016/j.cancergencyto.2006.08.001
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608