| Literature DB >> 17174926 |
Laura Santambrogio1, Jack L Strominger.
Abstract
One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).Entities:
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Year: 2006 PMID: 17174926 DOI: 10.1016/j.immuni.2006.11.007
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745