Literature DB >> 17174909

Chemotaxis: Cofilin in the driver's seat.

Sarah E Hitchcock-Degregori1.   

Abstract

A cell responds to a chemotactic signal by activating actin polymerization and forming a protrusion oriented towards the source. Recent work shows that the activity of cofilin, a protein that creates new barbed ends for actin filament elongation, amplifies and specifies the direction of the response in carcinoma cells.

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Year:  2006        PMID： 17174909     DOI： 10.1016/j.cub.2006.11.011

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

Review 1.  The regulation of cell motility and chemotaxis by phospholipid signaling.

Authors:  Verena Kölsch; Pascale G Charest; Richard A Firtel
Journal:  J Cell Sci       Date:  2008-03-01       Impact factor: 5.285

2.  Celastrus orbiculatus extract suppresses the epithelial-mesenchymal transition by mediating cytoskeleton rearrangement via inhibition of the Cofilin 1 signaling pathway in human gastric cancer.

Authors:  Haibo Wang; Hao Gu; Jun Feng; Yayun Qian; Lin Yang; Feng Jin; Xuanyi Wang; Jue Chen; Youyang Shi; Songhua Lu; Min Zhao; Yanqing Liu
Journal:  Oncol Lett       Date:  2017-06-23       Impact factor: 2.967

3.  Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade.

Authors:  Xun Wang; Shuang Zou; Tong Ren; Li-Jun Zhao; Li-Fei Yu; Xiang-Yu Li; Xin Yan; Li-Jun Zhang
Journal:  Int J Mol Med       Date:  2021-03-02       Impact factor: 4.101

4.  Expression of UGP2 and CFL1 expression levels in benign and malignant pancreatic lesions and their clinicopathological significance.

Authors:  Lingxiang Wang; Li Xiong; Zhengchun Wu; Xiongying Miao; Ziru Liu; Daiqiang Li; Qiong Zou; Zhulin Yang
Journal:  World J Surg Oncol       Date:  2018-01-18       Impact factor: 2.754
  4 in total

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