Literature DB >> 17174494

The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides.

I Montasser1, S Briançon2, H Fessi1.   

Abstract

Formulation of nanocapsules based on polyureas and polyamides have been tested using a patented process. This method based on polycondensation reaction of two complementary monomers and spontaneous formation of oil in water emulsion, is an alternative concept to the known technique based on the same type of reaction used for the formulation of microcapsules, and in which the lipophilic monomer was emulsified in the organic phase before the formation of the polymeric membrane. Nanocapsules can be prepared from different monomers. Wall based on cross-linked polymer contributes to the stability of nanocapsules during and after formulation. The permeability of the polymeric wall is related to its crystallinity and contributes to the growth of nanocapsule membrane by the diffusion of the hydrophilic monomers to get stable colloidal suspensions.

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Year:  2006        PMID: 17174494     DOI: 10.1016/j.ijpharm.2006.11.011

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  3 in total

1.  Analysis of process parameters affecting spray-dried oily core nanocapsules using factorial design.

Authors:  Tao Zhang; Bi-Botti C Youan
Journal:  AAPS PharmSciTech       Date:  2010-09-15       Impact factor: 3.246

Review 2.  Methods for the preparation and manufacture of polymeric nanoparticles.

Authors:  Christine Vauthier; Kawthar Bouchemal
Journal:  Pharm Res       Date:  2008-12-24       Impact factor: 4.200

3.  Preparation of polyamide nanocapsules of Aloe vera L. delivery with in vivo studies.

Authors:  Akbar Esmaeili; Maryam Ebrahimzadeh
Journal:  AAPS PharmSciTech       Date:  2014-10-02       Impact factor: 3.246

  3 in total

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