Literature DB >> 17173940

ent-Abietane diterpenoids from Isodon rubescens var. rubescens.

Sheng-Xiong Huang1, Jian-Xin Pu, Wei-Lie Xiao, Li-Mei Li, Zhi-Ying Weng, Yan Zhou, Quan-Bin Han, Shu-Lin Peng, Li-Sheng Ding, Li-Guang Lou, Han-Dong Sun.   

Abstract

ent-Abietane diterpenoids, hebeiabinins A-F (1-5), together with seven known diterpenoids were isolated from leaves of Isodon rubescens var. rubescens. The structures of 1-5 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. The diterpenoids isolated were evaluated for the cytotoxicity against A549, HT-29, and K562 tumor cells. Compound 5 was the most active with IC(50) value of 0.91 microM against A549 cells.

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Year:  2006        PMID: 17173940     DOI: 10.1016/j.phytochem.2006.11.007

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  1 in total

Review 1.  Isodon rubescens (Hemls.) Hara.: A Comprehensive Review on Traditional Uses, Phytochemistry, and Pharmacological Activities.

Authors:  Xufei Chen; Xufen Dai; Yinghai Liu; Xirui He; Gu Gong
Journal:  Front Pharmacol       Date:  2022-03-24       Impact factor: 5.810

  1 in total

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