| Literature DB >> 17173058 |
Luanne L Peters1, Raymond F Robledo, Carol J Bult, Gary A Churchill, Beverly J Paigen, Karen L Svenson.
Abstract
The mouse has been a powerful force in elucidating the genetic basis of human physiology and pathophysiology. From its beginnings as the model organism for cancer research and transplantation biology to the present, when dissection of the genetic basis of complex disease is at the forefront of genomics research, an enormous and remarkable mouse resource infrastructure has accumulated. This review summarizes those resources and provides practical guidelines for their use, particularly in the analysis of quantitative traits.Entities:
Mesh：
Year: 2007 PMID： 17173058 DOI： 10.1038/nrg2025
Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242