Literature DB >> 17173008

A survey of measures used for the prevention of postoperative endophthalmitis after cataract surgery in the United Kingdom.

P Gordon-Bennett1, A Karas, D Flanagan, C Stephenson, M Hingorani.   

Abstract

PURPOSE: This study investigates the current practice of United Kingdom (UK) ophthalmologists in perioperative antibiotic and antiseptic use in cataract surgery.
MATERIALS AND METHODS: A telephone interview survey was conducted with ophthalmic staff at all ophthalmic training units in the UK in October and November 2005.
RESULTS: The practices of a total of 800 consultants were ascertained. Preoperatively, 795 (99.4%) surgeons used povidone-iodine to prepare the skin. In all, 558 (69.8%) instilled 5 or 10% povidone-iodine in the conjunctival sac; 47 (5.9%) gave preoperative antibiotic eyedrops. Intraoperatively, intracameral antibiotics were given either as a bolus [80 (10.0%) intracameral cefuroxime, 29 (3.6%) intracameral vancomycin] or in the irrigating fluid [33 (4.1%) vancomycin]. 48 (6.0%) gave subconjunctival gentamycin only routinely, 531 (66.4%) gave subconjunctival cefuroxime, and 39 (4.9%) gave other subconjunctival antibiotics. A single dose of topical antibiotics was given by 134 (16.8%) surgeons. Postoperatively, 515 (64.4%) used a combination steroid and neomycin eyedrop, and 213 (26.6%) gave a separate steroid and chloramphenicol eyedrop.
CONCLUSIONS: This study reveals wide variations in the choice and duration of antibiotics used by UK ophthalmologists. The predominant methods of intraoperative prophylaxis are subconjunctival cefuroxime and intracameral cefuroxime. Most surgeons used a neomycin eyedrop for postoperative prophylaxis.

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Year:  2006        PMID: 17173008     DOI: 10.1038/sj.eye.6702675

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  9 in total

1.  Pharmacokinetics of subconjunctival injection of moxifloxacin in humans.

Authors:  Kazuki Matsuura
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-05-03       Impact factor: 3.117

2.  Safety of prophylactic intracameral moxifloxacin ophthalmic solution after cataract surgery in patients with penetrating keratoplasty.

Authors:  Osman Sevki Arslan; Ceyhun Arici; Mustafa Unal; Erdogan Cicik; Mehmet Serhat Mangan; Eray Atalay
Journal:  Int J Ophthalmol       Date:  2014-10-18       Impact factor: 1.779

3.  Comparison of the influence of intracameral gentamicin, gatifloxacin, and moxifloxacin on the corneal endothelium in a rabbit model.

Authors:  Shinichiro Kobayakawa; Yoshimune Hiratsuka; Yasuo Watabe; Akira Murakami; Tetsuo Tochikubo
Journal:  Jpn J Ophthalmol       Date:  2010-11-05       Impact factor: 2.447

4.  The comparison of clinical outcomes of endophthalmitis from fluoroquinolone-resistant and susceptible bacteria.

Authors:  Anita R Shirodkar; Harry W Flynn; Kyle Alliman; Geeta A Lalwani; Chrisfouad Alabiad; Andrew A Moshfeghi; Darlene Miller
Journal:  Clin Ophthalmol       Date:  2010-04-26

Review 5.  Intracameral cefuroxime: prophylaxis of postoperative endophthalmitis after cataract surgery.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2013-02       Impact factor: 9.546

6.  Risk factors for fluoroquinolone resistance in ocular cultures.

Authors:  Junsung Lee; Sangkyung Choi
Journal:  Korean J Ophthalmol       Date:  2015-01-22

7.  Comparison of Drug Concentrations in Human Aqueous Humor after the Administration of 0.3% Gatifloxacin Ophthalmic Gel, 0.3% Gatifloxacin and 0.5% Levofloxacin Ophthalmic Solutions.

Authors:  Wenting Ding; Weiling Ni; Huilian Chen; Jingqun Yuan; Xiaodan Huang; Zheng Zhang; Yao Wang; Yibo Yu; Ke Yao
Journal:  Int J Med Sci       Date:  2015-06-10       Impact factor: 3.738

8.  Role of intracameral antibiotics in endophthalmitis prophylaxis following-cataract surgery.

Authors:  Jeewan S Titiyal; Manpreet Kaur
Journal:  Indian J Ophthalmol       Date:  2020-05       Impact factor: 1.848

9.  Perioperative Antibiotics to Prevent Acute Endophthalmitis after Ophthalmic Surgery: A Systematic Review and Meta-Analysis.

Authors:  Jinzhu Huang; Xiaofang Wang; Xiaohong Chen; Qiuyue Song; Wen Liu; Laichun Lu
Journal:  PLoS One       Date:  2016-11-08       Impact factor: 3.240

  9 in total

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