Literature DB >> 17171330

[Replacement of the meniscus with a collagen implant (CMI)].

Ralf D Linke1, Michael Ulmer, Andreas B Imhoff.   

Abstract

OBJECTIVE: Replacement of an almost completely absent medial meniscus with a collagen implant (CMI), reconstruction of form and function of the medial meniscus, delay of the development of arthrosis deformans. INDICATIONS: Subtotal degenerative or traumatic loss of the medial meniscus, stable meniscal periphery, stable anterior and posterior meniscal insertions, joint with stable ligaments. CONTRAINDICATIONS: Complete loss of the medial meniscus. Untreated knee ligament instability. Extreme varus deformity. Extensive cartilaginous damage, i.e., levels IV and VI as described by Bauer and Jackson. Advanced unicompartmental or generalized arthrosis. Replacement of the lateral meniscus. SURGICAL TECHNIQUE: Standard anterior arthroscopy portals. Resection of the medial meniscus leaving a complete and stable outer rim. Revitalization of the periphery to promote healing. Measurement of defect size. Insertion and fixation of the CMI with nonresorbable suture material in inside-out technique. POSTOPERATIVE MANAGEMENT: Postoperative knee brace with limited motion in extension/ flexion of 0/0/60 degrees until week 4, 0/0/90 degrees until week 6. Continuous passive motion within the limits of motion from the 1st postoperative day, actively assisted physiotherapy. No weight bearing for 6 weeks, then increased weight bearing for 2 weeks until full weight bearing is achieved. Cycling can commence from 3 months postoperatively. Full sporting activity after 6 months.
RESULTS: 60 patients (19-68 years, average 41.6 years) with subtotal loss of the medial meniscus and varus morphotype were treated from January 2001 to May 2004 as part of a prospective, randomized, arthroscopically controlled study. The sample consisted of 30 patients with high tibial valgus osteotomy combined with implantation of a CMI, and 30 patients with valgization correction osteotomy only. The CMI had to be removed from one patient because of a dislocation. Evaluation on the Lysholm Score, IKDC (International Knee Documentation Committee), and subjective pain data revealed only slight, nonsignificant differences for 39 patients after 24 months (CMI and correction n = 23; correction only n = 16). The chondroprotective effect of the CMI in the long term remains to be seen.

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Year:  2006        PMID: 17171330     DOI: 10.1007/s00064-006-1188-9

Source DB:  PubMed          Journal:  Oper Orthop Traumatol        ISSN: 0934-6694            Impact factor:   1.154


  15 in total

Review 1.  Surgical treatment for early osteoarthritis. Part II: allografts and concurrent procedures.

Authors:  A H Gomoll; G Filardo; F K Almqvist; W D Bugbee; M Jelic; J C Monllau; G Puddu; W G Rodkey; P Verdonk; R Verdonk; S Zaffagnini; M Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-11-09       Impact factor: 4.342

2.  A multilayer tissue engineered meniscus substitute.

Authors:  Albana Ndreu Halili; Nesrin Hasirci; Vasif Hasirci
Journal:  J Mater Sci Mater Med       Date:  2014-01-23       Impact factor: 3.896

Review 3.  The current state of scaffolds for musculoskeletal regenerative applications.

Authors:  Benjamin D Smith; Daniel A Grande
Journal:  Nat Rev Rheumatol       Date:  2015-03-17       Impact factor: 20.543

Review 4.  Clinical outcomes and complications of a collagen meniscus implant: a systematic review.

Authors:  Alberto Grassi; Stefano Zaffagnini; Giulio Maria Marcheggiani Muccioli; Andrea Benzi; Maurilio Marcacci
Journal:  Int Orthop       Date:  2014-06-20       Impact factor: 3.075

Review 5.  MRI evaluation of a collagen meniscus implant: a systematic review.

Authors:  Stefano Zaffagnini; Alberto Grassi; Giulio Maria Marcheggiani Muccioli; Tommaso Bonanzinga; Marco Nitri; Federico Raggi; Giovanni Ravazzolo; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-07-04       Impact factor: 4.342

6.  Long-term outcomes of medial CMI implant versus partial medial meniscectomy in patients with concomitant ACL reconstruction.

Authors:  Erica Bulgheroni; Alberto Grassi; Paolo Bulgheroni; Giulio Maria Marcheggiani Muccioli; Stefano Zaffagnini; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-07-04       Impact factor: 4.342

Review 7.  Collagen meniscus implantation: a systematic review including rehabilitation and return to sports activity.

Authors:  Andrew Harston; John Nyland; Emily Brand; Mark McGinnis; David N M Caborn
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-06-22       Impact factor: 4.342

8.  One-year clinical and MR imaging outcome after partial meniscal replacement in stabilized knees using a collagen meniscus implant.

Authors:  M T Hirschmann; L Keller; A Hirschmann; L Schenk; R Berbig; U Lüthi; F Amsler; N F Friederich; M P Arnold
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-10-30       Impact factor: 4.342

Review 9.  Meniscal scaffolds: results and indications. A systematic literature review.

Authors:  Giuseppe Filardo; Luca Andriolo; Elizaveta Kon; Francesca de Caro; Maurilio Marcacci
Journal:  Int Orthop       Date:  2014-06-29       Impact factor: 3.075

Review 10.  Similar clinical outcomes following collagen or polyurethane meniscal scaffold implantation: a systematic review.

Authors:  Darby A Houck; Matthew J Kraeutler; John W Belk; Eric C McCarty; Jonathan T Bravman
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-01-16       Impact factor: 4.342

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