| Literature DB >> 17169502 |
Ramamoorthy Rajkumar1, Elavarasan Prem Kumar, Suresh Sudha, Bhojraj Suresh.
Abstract
The Celastrus oil, extracted from seeds of Celastrus paniculatus tested at 2 dose levels (1 and 1.5 g/kg), exhibited significant anxiolytic activity and did not produce tolerance. The non-sedative nature and reversal of buspirone induced behaviour (in open field exploration) point to the serotonergic mechanism underlying the anxiolysis, inspiring further research.Entities:
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Year: 2006 PMID： 17169502 DOI： 10.1016/j.fitote.2006.09.028
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882