Literature DB >> 1716890

Thrombospondin binds normally to glycoprotein IIIb deficient platelets.

B Kehrel1, A Kronenberg, B Schwippert, D Niesing-Bresch, U Niehues, D Tschöpe, J van de Loo, K J Clemetson.   

Abstract

Glycoprotein IIIb (GPIV, CD36) has been proposed as the platelet receptor for thrombospondin (TSP). We found two healthy blood donors, whose platelets were shown to be GPIIIb deficient. These platelets expressed endogeneous TSP as control platelets and their binding capacity for exogeneous TSP was the same. These results indicate that GPIIIb is not the major TSP receptor on platelets. However, it is not yet possible to exclude that in GPIIIb-deficient platelets other proteins may substitute for GPIIIb in TSP binding.

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Year:  1991        PMID： 1716890     DOI： 10.1016/0006-291x(91)91915-y

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  8 in total

1.  Thrombospondin-platelet interactions. Role of divalent cations, wall shear rate, and platelet membrane glycoproteins.

Authors:  F R Agbanyo; J J Sixma; P G de Groot; L R Languino; E F Plow
Journal:  J Clin Invest       Date:  1993-07       Impact factor: 14.808

2.  Association of thrombospondin-1 with the actin cytoskeleton of human thrombin-activated platelets through an alphaIIbbeta3- or CD36-independent mechanism.

Authors:  Anne Saumet; Nando de Jesus; Chantal Legrand; Véronique Dubernard
Journal:  Biochem J       Date:  2002-05-01       Impact factor: 3.857

3.  Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling.

Authors:  Jeff S Isenberg; Martin J Romeo; Christine Yu; Christine K Yu; Khauh Nghiem; Jude Monsale; Margaret E Rick; David A Wink; William A Frazier; David D Roberts
Journal:  Blood       Date:  2007-09-21       Impact factor: 22.113

4.  Interaction of thrombospondin with platelet glycoproteins GPIa-IIa and GPIIb-IIIa.

Authors:  M A Kowalska; G P Tuszynski
Journal:  Biochem J       Date:  1993-11-01       Impact factor: 3.857

5.  Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases.

Authors:  Claudia Pielsticker; Martin F Brodde; Lisa Raum; Kerstin Jurk; Beate E Kehrel
Journal:  Int J Mol Sci       Date:  2020-11-23       Impact factor: 5.923

6.  Molecular characterization of a novel Staphylococcus aureus surface protein (SasC) involved in cell aggregation and biofilm accumulation.

Authors:  Katrin Schroeder; Mario Jularic; Samantha M Horsburgh; Nina Hirschhausen; Claudia Neumann; Anne Bertling; Anja Schulte; Simon Foster; Beate E Kehrel; Georg Peters; Christine Heilmann
Journal:  PLoS One       Date:  2009-10-23       Impact factor: 3.240

7.  Age-Dependent Control of Collagen-Dependent Platelet Responses by Thrombospondin-1-Comparative Analysis of Platelets from Neonates, Children, Adolescents, and Adults.

Authors:  Katrin Herken; Martin Glauner; Stefanie C Robert; Matthias Maas; Sonja Zippel; Ulrike Nowak-Göttl; Barbara Zieger; Judith Lahav; Anke C Fender; Kerstin Jurk; Beate E Kehrel
Journal:  Int J Mol Sci       Date:  2021-05-05       Impact factor: 5.923

8.  Identification and characterization of a tumor cell receptor for CSVTCG, a thrombospondin adhesive domain.

Authors:  G P Tuszynski; V L Rothman; M Papale; B K Hamilton; J Eyal
Journal:  J Cell Biol       Date:  1993-01       Impact factor: 10.539
  8 in total

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