| Literature DB >> 17168611 |
Raquel P Herrera1, Valentina Sgarzani, Luca Bernardi, Francesco Fini, Daniel Pettersen, Alfredo Ricci.
Abstract
A study into the use of a chiral phase-transfer catalyst in conjunction with acetone cyanohydrin to effect the enantioselective formation of alpha-amino nitriles from alpha-amido sulfones is described. This novel catalytic asymmetric Strecker reaction is analyzed with regard to the possible mechanistic basis.Entities:
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Year: 2006 PMID： 17168611 DOI： 10.1021/jo061566u
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354