Literature DB >> 1716841

Characteristics of deoxycholic acid-induced histamine release from mast cells of guinea-pig rectocolonic mucosa and rat peritoneal cavity.

K H Peh1, B Y Wan, E S Assem.   

Abstract

Deoxycholic acid (DA) caused a dose-related release of histamine (HR) from mast cells of rat peritoneum (RPMC) and mucosal cells of guinea pig rectocolon (RCMC). In both cell populations, DA-induced HR was: (1) accompared by a parallel release of lactate dehydrogenase (LDH), (2) not affected by metabolic inhibitors, (3) dependent on time of incubation, temperature and pH, and affected by Ca++ concentration in RPMC but not in RCMC. DA-induced HR from RCMC may be involved in certain functional disorders of the colon.

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Year:  1991        PMID： 1716841     DOI： 10.1007/bf01993131

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  9 in total

Review 1.  Mast cell polymorphisms. Present concepts, future directions.

Authors:  D Befus; H Fujimaki; T D Lee; M Swieter
Journal:  Dig Dis Sci       Date:  1988-03       Impact factor: 3.199

2.  Changed sensitivity to antigen in a gut epithelium treated with bile salts.

Authors:  A W Baird; A W Cuthbert
Journal:  Br J Pharmacol       Date:  1985-03       Impact factor: 8.739

3.  Substance P and Arg-Pro-Lys-Pro-NH-C12-H25-induced mediator release from different mast cell subtypes of rat and guinea-pig.

Authors:  E S Assem; N S Ghanem; N A Abdullah; H Repke; J C Foreman; N A Hayes
Journal:  Immunopharmacology       Date:  1989 Mar-Apr

4.  Histamine content of rectal mucosa in ulcerative colitis.

Authors:  V Binder; E Hvidberg
Journal:  Gut       Date:  1967-02       Impact factor: 23.059

5.  Effects of calcium and pH on the mucosal damage produced by deoxycholic acid in the rat colon.

Authors:  J J Rafter; V W Eng; R Furrer; A Medline; W R Bruce
Journal:  Gut       Date:  1986-11       Impact factor: 23.059

6.  Ulcerative colitis: the result of an altered bacterial metabolism of bile acids or cholesterol.

Authors:  J D Bennet
Journal:  Med Hypotheses       Date:  1986-06       Impact factor: 1.538

7.  Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.

Authors:  A D Befus; F L Pearce; J Gauldie; P Horsewood; J Bienenstock
Journal:  J Immunol       Date:  1982-06       Impact factor: 5.422

8.  Involvement of prostaglandins in histamine-induced fluid and electrolyte secretion by rat colon.

Authors:  J Hardcastle; P T Hardcastle
Journal:  J Pharm Pharmacol       Date:  1988-02       Impact factor: 3.765

9.  Histamine augments colonic secretion in guinea pig distal colon.

Authors:  Y Z Wang; H J Cooke; H C Su; R Fertel
Journal:  Am J Physiol       Date:  1990-03
  9 in total
  2 in total

1.  Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes.

Authors:  Paolo Onori; Eugenio Gaudio; Antonio Franchitto; Gianfranco Alpini; Heather Francis
Journal:  World J Gastrointest Pathophysiol       Date:  2010-06-15

2.  The role of mast cell activation in cholestatic pruritus.

Authors:  W D Clements; D M O'Rourke; B J Rowlands; M Ennis
Journal:  Agents Actions       Date:  1994-06
  2 in total

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