Literature DB >> 1716839

Comparison of histamine release in cord blood and adult blood.

B W Nielsen1, T M Engberg, T Bjerke, P O Schiøtz.   

Abstract

Histamine release (HR) after stimulation with anti-IgE, concanavalin A (ConA) and Formyl-Met-Leu-Phe (FMLP) from 97 cord blood samples was compared to results obtained in identically treated blood samples from adults. The maximal HR obtained with anti-IgE did not differ significantly from the values obtained in adult blood, although a ten times higher concentration of anti-IgE was required for maximum release. Passive sensitization with IgE-rich plasma caused a significant increase in maximal anti-IgE-induced HR in the majority of cord blood samples, and the dose-response curve was similar to that obtained in adult blood. Challenge with ConA and FMLP caused a HR similar to that seen in adult blood, but the close correlation between anti-IgE- and concanavalin A-induced HR seen in adult blood was absent in cord blood.

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Year:  1991        PMID： 1716839     DOI： 10.1007/bf01993128

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  10 in total

1.  Time-course studies of immediate and delayed immune reactivity in patients with atopic dermatitis treated with herbal drugs.

Authors:  U Søderberg; B Windelborg Nielsen; C Schade Larsen; P O Schiøtz; K Thestrup-Pedersen
Journal:  Allergy       Date:  1990-11       Impact factor: 13.146

2.  Functional evaluation of the basophil/IgE system in the cord blood.

Authors:  A Miadonna; A Tedeschi; E Leggieri; G Motta; C Fabbri; M Froldi; M Agosti; M Lorini; A Marini; C Zanussi
Journal:  Int Arch Allergy Appl Immunol       Date:  1986

3.  Cord blood basophil releasability: evaluation of histamine release and leukotriene C4 generation.

Authors:  A Miadonna; E Leggieri; A Tedeschi; M Lorini; G Motta; G Lucci; M Froldi; A Marini; C Zanussi
Journal:  Int Arch Allergy Appl Immunol       Date:  1988

4.  Mechanism of action of concanavalin A on human basophils.

Authors:  R P Siraganian; P A Siragania
Journal:  J Immunol       Date:  1975-02       Impact factor: 5.422

5.  Sensitive glass microfibre-based histamine analysis for allergy testing in washed blood cells. Results compared with conventional leukocyte histamine release assay.

Authors:  P S Skov; H Mosbech; S Norn; B Weeke
Journal:  Allergy       Date:  1985-04       Impact factor: 13.146

6.  Influence of anions, cations and osmolarity on IgE-mediated histamine release from human basophils.

Authors:  W A Hook; R P Siraganian
Journal:  Immunology       Date:  1981-08       Impact factor: 7.397

7.  Basophil releasability in the newborn: factors limiting immunoglobulin E-mediated histamine release.

Authors:  G R Mendoza; K Minagawa; F B Orner; E R Stiehm
Journal:  Pediatrics       Date:  1982-02       Impact factor: 7.124

8.  Mechanism of histamine release by formyl methionine-containing peptides.

Authors:  R P Siraganian; W A Hook
Journal:  J Immunol       Date:  1977-12       Impact factor: 5.422

9.  Basophil histamine release in cord blood. Regulatory role of IgE.

Authors:  F Ebbesen; P S Skov; C Jensen; S Norn; I Søndergaard
Journal:  Allergy       Date:  1986-11       Impact factor: 13.146

10.  A new method for detecting histamine release.

Authors:  P Stahl Skov; S Norn; B Weeke
Journal:  Agents Actions       Date:  1984-04
  10 in total
  1 in total

1.  Hyperosmolarity selectively enhances IgE-receptor-mediated histamine release from human basophils.

Authors:  B W Nielsen; T Bjerke; T M Damsgaard; T Herlin; K Thestrup-Pedersen; P O Schiøtz
Journal:  Agents Actions       Date:  1992-03
  1 in total

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