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Literature DB >> 17167828

Pathophysiology of alcoholic pancreatitis: an overview.

Abstract

Use of alcohol is a worldwide habit regardless of socio-economic background. Heavy alcohol consumption is a potential risk factor for induction of pancreatitis. The current review cites the updated literature on the alcohol metabolism, its effects on gastrointestinal and pancreatic function and in causing pancreatic injury, genetic predisposition of alcohol induced pancreatitis. Reports describing prospective mechanisms of action of alcohol activating the signal transduction pathways, induction of oxidative stress parameters through the development of animal models are being presented.

Entities: Chemical Disease

Mesh：

Substances：
Ethanol

Year: 2006 PMID： 17167828 PMCID： PMC4087585 DOI： 10.3748/wjg.v12.i46.7421

Source DB: PubMed Journal: World J Gastroenterol ISSN： 1007-9327 Impact factor: 5.742

96 in total

1. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis.

Authors: H Witt; W Luck; H C Hennies; M Classen; A Kage; U Lass; O Landt; M Becker
Journal: Nat Genet Date: 2000-06 Impact factor: 38.330

Review 2. [Effects of alcohol on the upper gastrointestinal tract and the pancreas--an up-to-date overview].

Authors: S V Siegmund; M V Singer
Journal: Z Gastroenterol Date: 2005-08 Impact factor: 2.000

3. The influence of ethanol on pancreatic blood flow in cats with chronic pancreatitis.

Authors: A L Widdison; C Alvarez; M Schwarz; H A Reber
Journal: Surgery Date: 1992-08 Impact factor: 3.982

4. Action of beer and its ingredients on gastric acid secretion and release of gastrin in humans.

Authors: M V Singer; S Teyssen; V E Eysselein
Journal: Gastroenterology Date: 1991-10 Impact factor: 22.682

5. Ethanol-induced alterations in pancreatic blood flow in conscious dogs.

Authors: L D Horwitz; J H Myers
Journal: Circ Res Date: 1982-02 Impact factor: 17.367

6. Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis.

Authors: K Kuwata; M Hirota; H Sugita; M Kai; N Hayashi; M Nakamura; T Matsuura; N Adachi; I Nishimori; M Ogawa
Journal: J Gastroenterol Date: 2001-09 Impact factor: 7.527

7. Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis?

Authors: Franco Fortunato; Xiaoying Deng; Lawrence K Gates; Craig J McClain; Daniel Bimmler; Rolf Graf; David C Whitcomb
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2005-06-23 Impact factor: 4.052

8. Metabolism of ethanol by rat pancreatic acinar cells.

Authors: P S Haber; M V Apte; T L Applegate; I D Norton; M A Korsten; R C Pirola; J S Wilson
Journal: J Lab Clin Med Date: 1998-10

9. Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies.

Authors: I Johansson; G Ekström; B Scholte; D Puzycki; H Jörnvall; M Ingelman-Sundberg
Journal: Biochemistry Date: 1988-03-22 Impact factor: 3.162

10. Ethanol differentially regulates NF-kappaB activation in pancreatic acinar cells through calcium and protein kinase C pathways.

Authors: Anna S Gukovskaya; Saeed Hosseini; Akihiko Satoh; Jason H Cheng; Kyung J Nam; Ilya Gukovsky; Stephen J Pandol
Journal: Am J Physiol Gastrointest Liver Physiol Date: 2003-09-04 Impact factor: 4.052

15 in total

1. Alcohol Intoxication and the Postburn Gastrointestinal Hormonal Response.

Authors: Juan-Pablo Idrovo; Jill A Shults; Brenda J Curtis; Michael M Chen; Elizabeth J Kovacs
Journal: J Burn Care Res Date: 2019-10-16 Impact factor: 1.845

Review 2. Food-Induced Acute Pancreatitis.

Authors: Murli Manohar; Alok K Verma; Sathisha Upparahalli Venkateshaiah; Hemant Goyal; Anil Mishra
Journal: Dig Dis Sci Date: 2017-10-30 Impact factor: 3.199

3. Comparative Analysis of Early Clinical Features and Complications of Different Types of Acute Pancreatitis.

Authors: Hongsheng Wu; Keqiang Ma; Biling Liao; Tengfei Ji; Shengmin Zhang; Tiansheng Cao
Journal: Oxid Med Cell Longev Date: 2022-06-25 Impact factor: 7.310

Review 4. An update on pancreatic pathophysiology (do we have to rewrite pancreatic pathophysiology?).

Authors: Heinz F Hammer
Journal: Wien Med Wochenschr Date: 2014-01-28

Review 5. Beer and its non-alcoholic compounds: role in pancreatic exocrine secretion, alcoholic pancreatitis and pancreatic carcinoma.

Authors: Andreas Gerloff; Manfred V Singer; Peter Feick
Journal: Int J Environ Res Public Health Date: 2010-03-15 Impact factor: 3.390

6. Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats.

Authors: Ali Keshavarzian; Ashkan Farhadi; Christopher B Forsyth; Jayanthi Rangan; Shriram Jakate; Maliha Shaikh; Ali Banan; Jeremy Z Fields
Journal: J Hepatol Date: 2008-12-29 Impact factor: 25.083