Literature DB >> 17167350

Survival of critically ill patients hospitalized in and out of intensive care.

Elisheva Simchen1, Charles L Sprung, Noya Galai, Yana Zitser-Gurevich, Yaron Bar-Lavi, Leon Levi, Fabio Zveibil, Micha Mandel, George Mnatzaganian, Nethanel Goldschmidt, Anat Ekka-Zohar, Inbal Weiss-Salz.   

Abstract

OBJECTIVE: A lack of intensive care units beds in Israel results in critically ill patients being treated outside of the intensive care unit. The survival of such patients is largely unknown. The present study's objective was to screen entire hospitals for newly deteriorated patients and compare their survival in and out of the intensive care unit.
DESIGN: A priori developed intensive care unit admission criteria were used to screen, during 2 wks, the patient population for eligible incident patients. A screening team visited every hospital ward of five acute care hospitals daily. Eligible patients were identified among new admissions in the emergency department and among hospitalized patients who acutely deteriorated. Patients were followed for 30 days for mortality regardless of discharge.
SETTING: Five acute care hospitals. PATIENTS: A total of 749 newly deteriorated patients.
INTERVENTIONS: None.
MEASUREMENTS AND MAIN RESULTS: Crude survival of patients in and out of the intensive care unit was compared by Kaplan-Meier curves, and Cox models were constructed to adjust the survival comparisons for residual case-mix differences. A total of 749 newly deteriorated patients were identified among 44,000 patients screened (1.7%). Of these, 13% were admitted to intensive care unit, 32% to special care units, and 55% to regular departments. Intensive care unit patients had better early survival (0-3 days) relative to regular departments (p=.0001) in a Cox multivariate model. Early advantage of intensive care was most pronounced among patients who acutely deteriorated while on hospital wards rather than among newly admitted patients.
CONCLUSIONS: Only a small proportion of eligible patients reach the intensive care unit, and early admission is imperative for their survival advantage. As intensive care unit benefit was most pronounced among those deteriorating on hospital wards, intensive care unit triage decisions should be targeted at maximizing intensive care unit benefit by early admitting patients deteriorating on hospital wards.

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Year:  2007        PMID: 17167350     DOI: 10.1097/01.CCM.0000253407.89594.15

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  34 in total

1.  Functional status does not predict complicated clinical course in older adults in the emergency department with infection.

Authors:  Jeffrey M Caterino; Robert A Murden; Kurt B Stevenson
Journal:  J Am Geriatr Soc       Date:  2012-01-27       Impact factor: 5.562

2.  Identifying infected emergency department patients admitted to the hospital ward at risk of clinical deterioration and intensive care unit transfer.

Authors:  Maura Kennedy; Nina Joyce; Michael D Howell; J Lawrence Mottley; Nathan I Shapiro
Journal:  Acad Emerg Med       Date:  2010-10       Impact factor: 3.451

3.  Optimal control of ICU patient discharge: from theory to implementation.

Authors:  Fermín Mallor; Cristina Azcárate; Julio Barado
Journal:  Health Care Manag Sci       Date:  2015-03-13

4.  Relationships among initial hospital triage, disease progression and mortality in community-acquired pneumonia.

Authors:  Samuel M Brown; Jason P Jones; Dominik Aronsky; Barbara E Jones; Michael J Lanspa; Nathan C Dean
Journal:  Respirology       Date:  2012-11       Impact factor: 6.424

5.  The Effect of Intensive Care Unit Admission Patterns on Mortality-based Critical Care Performance Measures.

Authors:  Ian J Barbash; Tri Q Le; Francis Pike; Amber E Barnato; Derek C Angus; Jeremy M Kahn
Journal:  Ann Am Thorac Soc       Date:  2016-06

6.  Cost effectiveness of intensive care in a low resource setting: A prospective cohort of medical critically ill patients.

Authors:  Hajrunisa Cubro; Rabija Somun-Kapetanovic; Guillaume Thiery; Daniel Talmor; Ognjen Gajic
Journal:  World J Crit Care Med       Date:  2016-05-04

7.  "Deterioration to Door Time": An Exploratory Analysis of Delays in Escalation of Care for Hospitalized Patients.

Authors:  Christopher B Sankey; Gail McAvay; Jonathan M Siner; Carol L Barsky; Sarwat I Chaudhry
Journal:  J Gen Intern Med       Date:  2016-03-11       Impact factor: 5.128

8.  A costly separation between withdrawing and withholding treatment in intensive care.

Authors:  Dominic Wilkinson; Julian Savulescu
Journal:  Bioethics       Date:  2012-07-05       Impact factor: 1.898

9.  Triage of intensive care patients: identifying agreement and controversy.

Authors:  Charles L Sprung; Marion Danis; Gaetano Iapichino; Antonio Artigas; Jozef Kesecioglu; Rui Moreno; Anne Lippert; J Randall Curtis; Paula Meale; Simon L Cohen; Mitchell M Levy; Robert D Truog
Journal:  Intensive Care Med       Date:  2013-08-08       Impact factor: 17.440

10.  Reasons for refusal of admission to intensive care and impact on mortality.

Authors:  Gaetano Iapichino; Davide Corbella; Cosetta Minelli; Gary H Mills; Antonio Artigas; David L Edbooke; Angelo Pezzi; Jozef Kesecioglu; Nicolò Patroniti; Mario Baras; Charles L Sprung
Journal:  Intensive Care Med       Date:  2010-06-09       Impact factor: 17.440

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