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Literature DB >> 17165913

Synthesis of 48 disaccharide building blocks for the assembly of a heparin and heparan sulfate oligosaccharide library.

Lung-Dai Lu¹, Chi-Rung Shie, Suvarn S Kulkarni, Guan-Rong Pan, Xin-An Lu, Shang-Cheng Hung.

Abstract

[Structure: see text] An efficient synthesis of the entire set of suitably protected 48 disaccharide building blocks for the assembly of a heparin and heparan sulfate oligosaccharide library is described here.

Entities: Chemical

Mesh：

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Year: 2006 PMID： 17165913 DOI： 10.1021/ol062464t

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

15 in total

1. Towards the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks.

Authors: Akihiro Saito; Masahiro Wakao; Hiroshi Deguchi; Aya Mawatari; Michael Sobel; Yasuo Suda
Journal: Tetrahedron Date: 2010-05-29 Impact factor: 2.457

2. Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds.

Authors: Arjun Raghuraman; Muhammad Riaz; Michael Hindle; Umesh R Desai
Journal: Tetrahedron Lett Date: 2007-09-17 Impact factor: 2.415

3. Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions.

Authors: Zhen Wang; Yongmei Xu; Bo Yang; Gopinath Tiruchinapally; Bin Sun; Renpeng Liu; Steven Dulaney; Jian Liu; Xuefei Huang
Journal: Chemistry Date: 2010-07-26 Impact factor: 5.236

4. Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host-cell interaction.

Authors: Yu-Peng Hu; Shu-Yi Lin; Cheng-Yen Huang; Medel Manuel L Zulueta; Jing-Yuan Liu; Wen Chang; Shang-Cheng Hung
Journal: Nat Chem Date: 2011-06-19 Impact factor: 24.427

Synthesis of 48 disaccharide building blocks for the assembly of a heparin and heparan sulfate oligosaccharide library.

1. Towards the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks.

2. Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds.

3. Preactivation-based, one-pot combinatorial synthesis of heparin-like hexasaccharides for the analysis of heparin-protein interactions.

4. Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host-cell interaction.

5. Automated Solid Phase Assisted Synthesis of a Heparan Sulfate Disaccharide Library.

6. Chemical synthesis of the outer core oligosaccharide of Escherichia coli R3 and immunological evaluation.

7. Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies.

8. Sugar Chips immobilized with synthetic sulfated disaccharides of heparin/heparan sulfate partial structure.

9. Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides.

Review 10. Strategies in synthesis of heparin/heparan sulfate oligosaccharides: 2000-present.