Literature DB >> 17165008

[Bridging peripheral nerve defects by means of nerve conduits].

J Lohmeyer1, S Zimmermann, B Sommer, H-G Machens, T Lange, P Mailänder.   

Abstract

BACKGROUND: The nerve autograft is the gold standard for the reconstruction of peripheral nerve defects. In short gaps, nerve repair by means of tubulization has become an alternative. This technique is discussed based on the current literature and our own experience. PATIENTS AND METHODS: Nerve reconstruction by means of tubulization was performed in 11 patients. Nerve gaps in the hand of up to 18 mm were reconstructed. Sensibility was assessed using static and dynamic two point discrimination (s-, d2PD) and monofilament testing 3, 6 and 12 months postoperatively.
RESULTS: Three out of 11 patients complained of a temporary foreign body sensation in the area of the implant; this was persistent in one case. Four out of six patients showed excellent results with s2PD of <or=7 mm (Highet S4) assessed 12 months postoperatively. One patient regained no (s2PD>15 mm, S0), another poor sensibility (s2PD 15 mm, S3). D2PD and monofilament testing confirmed these results.
CONCLUSIONS: Nerve reconstruction by means of tubulization seems to be a suitable method for certain indications in the reconstruction of short defects of digital and palmar nerves. Donor site morbidity can be avoided. Similarly to nerve transplantation, the operation requires microsurgical skills.

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Year:  2007        PMID: 17165008     DOI: 10.1007/s00104-006-1269-1

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  23 in total

Review 1.  Nerve conduits.

Authors:  John S Taras; Vipul Nanavati; Pamela Steelman
Journal:  J Hand Ther       Date:  2005 Apr-Jun       Impact factor: 1.950

2.  Neurotube for facial nerve repair.

Authors:  Massimo Navissano; Fabrizio Malan; Riccardo Carnino; Bruno Battiston
Journal:  Microsurgery       Date:  2005       Impact factor: 2.425

3.  A study of nerve regeneration across synthetic (Maxon) and biologic (collagen) nerve conduits for nerve gaps up to 5 cm in the primate.

Authors:  S E Mackinnon; A L Dellon
Journal:  J Reconstr Microsurg       Date:  1990-04       Impact factor: 2.873

Review 4.  Nerve regeneration through artificial tubular implants.

Authors:  R D Fields; J M Le Beau; F M Longo; M H Ellisman
Journal:  Prog Neurobiol       Date:  1989       Impact factor: 11.685

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Journal:  J Hand Ther       Date:  1998 Jul-Sep       Impact factor: 1.950

6.  Evaluation of peripheral nerve regeneration across an 80-mm gap using a polyglycolic acid (PGA)--collagen nerve conduit filled with laminin-soaked collagen sponge in dogs.

Authors:  T Toba; T Nakamura; A K Lynn; K Matsumoto; S Fukuda; M Yoshitani; Y Hori; Y Shimizu
Journal:  Int J Artif Organs       Date:  2002-03       Impact factor: 1.595

7.  A randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans.

Authors:  R A Weber; W C Breidenbach; R E Brown; M E Jabaley; D P Mass
Journal:  Plast Reconstr Surg       Date:  2000-10       Impact factor: 4.730

8.  Regeneration of peripheral nerve gaps with a polyglycolic acid-collagen tube.

Authors:  Yuji Inada; Shigeru Morimoto; Yoshinori Takakura; Tatsuo Nakamura
Journal:  Neurosurgery       Date:  2004-09       Impact factor: 4.654

9.  Results of primary nerve repair in the upper extremity.

Authors:  P Mailänder; A Berger; E Schaller; K Ruhe
Journal:  Microsurgery       Date:  1989       Impact factor: 2.425

10.  Tubular repair of the median or ulnar nerve in the human forearm: a 5-year follow-up.

Authors:  G Lundborg; B Rosén; L Dahlin; J Holmberg; I Rosén
Journal:  J Hand Surg Br       Date:  2004-04
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  6 in total

Review 1.  Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair.

Authors:  David J Gerth; Jun Tashiro; Seth R Thaller
Journal:  World J Clin Cases       Date:  2015-02-16       Impact factor: 1.337

Review 2.  Implantable Biomaterials for Peripheral Nerve Regeneration-Technology Trends and Translational Tribulations.

Authors:  Angela Sanchez Rezza; Yalcin Kulahci; Vijay S Gorantla; Fatih Zor; Norman M Drzeniek
Journal:  Front Bioeng Biotechnol       Date:  2022-04-27

3.  Modern concepts in facial nerve reconstruction.

Authors:  Gerd F Volk; Mira Pantel; Orlando Guntinas-Lichius
Journal:  Head Face Med       Date:  2010-11-01       Impact factor: 2.151

4.  Collagen tube conduits in peripheral nerve repair: a retrospective analysis.

Authors:  Kirk J Wangensteen; Loree K Kalliainen
Journal:  Hand (N Y)       Date:  2009-11-24

5.  Recent advances and developments in neural repair and regeneration for hand surgery.

Authors:  Mukai Chimutengwende-Gordon; Wasim Khan
Journal:  Open Orthop J       Date:  2012-02-23

6.  Sensory recovery outcome after digital nerve repair in relation to different reconstructive techniques: meta-analysis and systematic review.

Authors:  Felix J Paprottka; Petra Wolf; Yves Harder; Yasmin Kern; Philipp M Paprottka; Hans-Günther Machens; Jörn A Lohmeyer
Journal:  Plast Surg Int       Date:  2013-07-30
  6 in total

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