Literature DB >> 17164118

Role of obesity, insulin resistance, and steatosis in hepatitis C virus infection.

Puneet Puri1, Arun J Sanyal.   

Abstract

Hepatitis C, nonalcoholic fatty liver characterized by hepatic steatosis, and obesity inflict significant health and economic burdens on the Western world. Insulin resistance is the key player in these disease processes. Complex interplay between these conditions results in the ultimate phenotype of liver disease. This article focuses on the current understanding of host and viral interactions as well as on consequent clinical implications.

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Year:  2006        PMID: 17164118     DOI: 10.1016/j.cld.2006.08.002

Source DB:  PubMed          Journal:  Clin Liver Dis        ISSN: 1089-3261            Impact factor:   6.126


  5 in total

1.  Chronic hepatitis c genotype-4 infection: role of insulin resistance in hepatocellular carcinoma.

Authors:  Amal A Mohamed; Samah A Loutfy; James D Craik; Abdel Gawad M Hashem; Ibrahem Siam
Journal:  Virol J       Date:  2011-11-01       Impact factor: 4.099

2.  Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture.

Authors:  Ramazan Kurt; Partha K Chandra; Fatma Aboulnasr; Rajesh Panigrahi; Pauline Ferraris; Yucel Aydin; Krzysztof Reiss; Tong Wu; Luis A Balart; Srikanta Dash
Journal:  PLoS One       Date:  2015-05-11       Impact factor: 3.240

3.  Demographic profile, host, disease & viral predictive factors of response in patients with chronic hepatitis C virus infection at a tertiary care hospital in north India.

Authors:  Sreejith Vasudevan; Amit Kavimandan; Nancy Kalra; Baibaswata Nayak; Bhaskar Thakur; Prasenjit Das; Siddhartha Datta Gupta; Subrat Kumar Panda; Subrat Kumar Acharya
Journal:  Indian J Med Res       Date:  2016-03       Impact factor: 2.375

4.  Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture.

Authors:  Feyza Gunduz; Fatma M Aboulnasr; Partha K Chandra; Sidhartha Hazari; Bret Poat; Darren P Baker; Luis A Balart; Srikanta Dash
Journal:  Virol J       Date:  2012-08-03       Impact factor: 4.099

5.  In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism.

Authors:  Kaelan Gobeil Odai; Conor O'Dwyer; Rineke Steenbergen; Tyler A Shaw; Tyler M Renner; Peyman Ghorbani; Mojgan Rezaaifar; Shauna Han; Marc-André Langlois; Angela M Crawley; Rodney S Russell; John P Pezacki; D Lorne Tyrrell; Morgan D Fullerton
Journal:  Viruses       Date:  2020-01-16       Impact factor: 5.048

  5 in total

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