Antioxidants in dermocosmetology: from the laboratory to clinical application.

Oxygen situated in cutaneous cells can be activated by light. This makes the integumentary apparatus particularly vulnerable to oxidative damage and is responsible for the immediate cutaneous damage that is the basis of late phenomena, such as photo-induced ageing and tumours. Thus, the cosmetic industry has undertaken research and development into antioxidant-based products able to protect the skin from the effect of pro-oxidizing noxae. This review re-examines both antioxidants suitable for dermatological application and skin care products with antioxidant capacity, as well as the laboratory methods used to evaluate the effects and in vivo efficacy of antioxidants.