Literature DB >> 17163916

Fat injections for facial rejuvenation: 17 years experience in 1720 patients.

D Dasiou-Plakida1.   

Abstract

BACKGROUND: Autologous adipose tissue has been proved to be an excellent filling material. Fat injections can correct cosmetic defects that are caused by loss of subcutaneous tissue, such as atrophy of the face due to significant weight loss, wrinkles and facial involution due to ageing.
OBJECTIVE: To evaluate the safety and long-term results of facial rejuvenation by autologous fat injections using the fine-needle technique to inject fat and frozen fat for repeating the implantation procedure.
METHOD: Patients were evaluated clinically and photographically. Extraction, processing and implantation of fat were performed using an anaerobic technique. The fat was harvested by tumescent liposuction, using syringes and small diameter blunt-tip cannulas (2-3 mm). After washing the collected fat in normal saline it was centrifuged, transferred to small syringes (1-2.5 mL diameter) and then injected subcutaneously using fine needles of 21-23 G. Hypercorrection was avoided, so one or two repetitions of the fat injections were usually necessary, at intervals of at least 1 month, in order to achieve the desired cosmetic result. Using frozen fat simplified repeat fat implantation.
RESULTS: The clinical long-term follow-up of 1720 patients up to 17 years is presented. Absorption of the injected fat was estimated at 40-60%. The absorption rate varied a lot in each case. Long-term follow-up proved that final correction after two or more repetitions of frozen fat injections, persisted for many years, the longest proved to be more than 12 years.
CONCLUSIONS: The advantages of the fine-needle technique for fat grafting were very important: more accurate and refined work, less painful injections, no scars at needle puncture points, early treatment of small defects, and the facility to treat multiple sites, even the entire face, in one session. There were no major complications. Oedema and sometimes echymoses at the donor site for 6-10 days and slight bruising at the injected areas for 3-5 days are the disadvantages of the procedure.

Entities:  

Year:  2003        PMID: 17163916     DOI: 10.1111/j.1473-2130.2004.00060.x

Source DB:  PubMed          Journal:  J Cosmet Dermatol        ISSN: 1473-2130            Impact factor:   2.696


  8 in total

Review 1.  Particle size in fat graft retention: A review on the impact of harvesting technique in lipofilling surgical outcomes.

Authors:  Trent M Gause; Russell E Kling; Wesley N Sivak; Kacey G Marra; J Peter Rubin; Lauren E Kokai
Journal:  Adipocyte       Date:  2014-12-10       Impact factor: 4.534

2.  Lipofilling: A New Therapeutic Option for the Treatment of Lupus Panniculitis-Induced Atrophy.

Authors:  Laura Polivka; Marc Revol; Maxime Battistella; Hervé Bachelez
Journal:  Case Rep Dermatol       Date:  2016-11-15

Review 3.  Procedure, applications, and outcomes of autologous fat grafting.

Authors:  Francesco Simonacci; Nicolò Bertozzi; Michele Pio Grieco; Eugenio Grignaffini; Edoardo Raposio
Journal:  Ann Med Surg (Lond)       Date:  2017-06-27

4.  Fat Injection and Its Clinical Applications.

Authors:  Chetan Satish
Journal:  J Cutan Aesthet Surg       Date:  2022 Apr-Jun

5.  Histological Analysis of the Effect of Nanofat Grafting in Scar Rejuvenation.

Authors:  Dasari Madhu VinayKumar; Subair Mohsina; Satyaswarup Tripathy; Ramesh Kumar Sharma; Alka Bhatia
Journal:  J Cutan Aesthet Surg       Date:  2022 Apr-Jun

Review 6.  Facial Fat Grafting (FFG): Worth the Risk? A Systematic Review of Complications and Critical Appraisal.

Authors:  Luigi Schiraldi; Gianluca Sapino; Joachim Meuli; Michele Maruccia; Mario Cherubino; Wassim Raffoul; Pietro G di Summa
Journal:  J Clin Med       Date:  2022-08-11       Impact factor: 4.964

7.  Autologous Fat Transfer for Facial Rejuvenation: A Systematic Review on Technique, Efficacy, and Satisfaction.

Authors:  Jan-Willem Groen; Todor K Krastev; Juliette Hommes; Janneke A Wilschut; Marco J P F Ritt; Rene R J W van der Hulst
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-12-22

8.  1470-nm Radial fiber-assisted liposuction for body contouring and facial fat grafting.

Authors:  Lior Heller; Shaked Menashe; Lori Plonski; Andre Ofek; Jason N Pozner
Journal:  J Cosmet Dermatol       Date:  2022-02-02       Impact factor: 2.189

  8 in total

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