Literature DB >> 17163661

Targeting translation in hypoxic tumors.

David Ron1, Alan G Hinnebusch.   

Abstract

Recent insight into how mammalian cells adapt their translational machinery to hypoxic conditions raises the possibility of targeting components of the regulatory networks involved to selectively inhibit metabolically compromised tumor cells and possibly manipulate a broad range of other physiological processes.

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Year:  2006        PMID: 17163661     DOI: 10.1021/cb600125y

Source DB:  PubMed          Journal:  ACS Chem Biol        ISSN: 1554-8929            Impact factor:   5.100


  1 in total

1.  Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer.

Authors:  Malin Lando; Marit Holden; Linn C Bergersen; Debbie H Svendsrud; Trond Stokke; Kolbein Sundfør; Ingrid K Glad; Gunnar B Kristensen; Heidi Lyng
Journal:  PLoS Genet       Date:  2009-11-13       Impact factor: 5.917

  1 in total

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