| Literature DB >> 17163657 |
Sarah F Roush1, Frank J Slack.
Abstract
Small, inhibitory RNA molecules called microRNAs cause large decreases in target protein levels through a post-transcriptional mechanism. Until recently, it was believed this mechanism operated almost exclusively at a step in translation. However, new work has revealed that microRNAs have a second, post-transcriptional mechanism that accelerates the rate of deadenylation, the initial step of mRNA decay.Mesh：
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Year: 2006 PMID： 17163657 DOI： 10.1021/cb600138j
Source DB: PubMed Journal: ACS Chem Biol ISSN： 1554-8929 Impact factor: 5.100