Literature DB >> 17162609

Intravitreal triamcinolone acetonide treatment for serpiginous choroiditis.

Ufuk Adigüzel1, Ayça Sari, Cengiz Ozmen, Ozay Oz.   

Abstract

PURPOSE: To report the efficacy of intravitreal triamcinolone acetonide injection for acute treatment of a patient with serpiginous choroiditis.
METHODS: A 50-year-old male patient with serpiginous choroiditis presenting with the complaint of decreased visual acuity in his right eye for the last 10 days. The best corrected visual acuity (BCVA) of the patient was counting finger from 1 meter. Fundus examination and fundus fluorescein angiography of right eye revealed active macular choroiditis in right eye. Intravitreal triamcinolone acetonide (4 mg/0.1 ml) was injected into vitreous, and the patient was followed with visual acuity testing, intraocular pressure measurement, and fundus examination, including fundus fluorescein angiography.
RESULTS: Visual acuity of the patient improved to 20/100 after 2 weeks in spite of the triamcinolone crystals, and to 20/50 after 4 weeks with a single dose intravitreal triamcinolone acetonide injection. Complete resolution of the active lesion has been maintained during the 6 months of follow-up.
CONCLUSIONS: Single dose intravitreal triamcinolone acetonide injection is sufficient for controlling the active lesions in serpiginous choroiditis. It needs further evaluation as an alternative treatment for achieving rapid and significant visual acuity recovery.

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Year:  2006        PMID: 17162609     DOI: 10.1080/09273940601025974

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  5 in total

1.  Steroid differentiation: the safety profile of various steroids on retinal cells in vitro and their implications for clinical use (an American Ophthalmological Society thesis).

Authors:  Baruch D Kuppermann; Leandro Cabral Zacharias; M Cristina Kenney
Journal:  Trans Am Ophthalmol Soc       Date:  2014-07

Review 2.  Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis.

Authors:  Hossein Nazari Khanamiri; Narsing A Rao
Journal:  Surv Ophthalmol       Date:  2013-03-27       Impact factor: 6.048

3.  Intravitreal triamcinolone for intraocular inflammation and associated macular edema.

Authors:  Steven M Couch; Sophie J Bakri
Journal:  Clin Ophthalmol       Date:  2009-06-02

4.  Efficacy of reduced dose of intravitreal triamcinolone acetonide in a case of active serpiginous choroiditis.

Authors:  Avirupa Ghose; Promod S Bhende; Jyotirmoy Biswas
Journal:  Indian J Ophthalmol       Date:  2016-09       Impact factor: 1.848

Review 5.  Enigma of serpiginous choroiditis.

Authors:  Parthopratim Dutta Majumder; Jyotirmay Biswas; Amod Gupta
Journal:  Indian J Ophthalmol       Date:  2019-03       Impact factor: 1.848

  5 in total

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