| Literature DB >> 17161367 |
Anton Arkhipov1, Peter L Freddolino, Klaus Schulten.
Abstract
We report a study of the structural dynamics of viral capsids, simulated on a microsecond timescale, by employing a coarse-graining molecular dynamics method. The method was calibrated against an all-atom simulation of one complete virus. Among the studied capsids, some collapsed rapidly, while others were found to be stable. Interlocking between coat proteins is found to be a key factor determining the stability of the capsids.Entities:
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Year: 2006 PMID： 17161367 DOI： 10.1016/j.str.2006.10.003
Source DB: PubMed Journal: Structure ISSN： 0969-2126 Impact factor: 5.006