Literature DB >> 17160056

The business of developing antibacterials.

Jeffrey L Fox.   

Abstract

Although some dazzling technical approaches have fallen short, dozens of small companies and a few major pharmas seek new products for this medically crucial, modest-growth market.

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Year:  2006        PMID： 17160056     DOI： 10.1038/nbt1206-1521

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


  16 in total

Review 1.  Novel approaches to developing new antibiotics for bacterial infections.

Authors:  A R M Coates; Y Hu
Journal:  Br J Pharmacol       Date:  2007-08-20       Impact factor: 8.739

2.  Transitions between closed and open conformations of TolC: the effects of ions in simulations.

Authors:  Robert Schulz; Ulrich Kleinekathöfer
Journal:  Biophys J       Date:  2009-04-22       Impact factor: 4.033

3.  Total synthesis of (-)-4,8,10-tridesmethyl telithromycin.

Authors:  Venkata Velvadapu; Tapas Paul; Bharat Wagh; Ian Glassford; Charles DeBrosse; Rodrigo B Andrade
Journal:  J Org Chem       Date:  2011-08-24       Impact factor: 4.354

4.  Desmethyl Macrolide Analogues to Address Antibiotic Resistance: Total Synthesis and Biological Evaluation of 4,8,10-Tridesmethyl Telithromycin.

Authors:  Venkata Velvadapu; Tapas Paul; Bharat Wagh; Dorota Klepacki; Olgun Guvench; Alexander Mackerell; Rodrigo B Andrade
Journal:  ACS Med Chem Lett       Date:  2011-01-13       Impact factor: 4.345

5.  Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.

Authors:  Ian Glassford; Christiana N Teijaro; Samer S Daher; Amy Weil; Meagan C Small; Shiv K Redhu; Dennis J Colussi; Marlene A Jacobson; Wayne E Childers; Bettina Buttaro; Allen W Nicholson; Alexander D MacKerell; Barry S Cooperman; Rodrigo B Andrade
Journal:  J Am Chem Soc       Date:  2016-02-26       Impact factor: 15.419

6.  Changes in the use of broad-spectrum antibiotics after cefepime shortage: a time series analysis.

Authors:  C Plüss-Suard; A Pannatier; C Ruffieux; A Kronenberg; K Mühlemann; G Zanetti
Journal:  Antimicrob Agents Chemother       Date:  2011-11-28       Impact factor: 5.191

7.  Identification, characterization, and recombinant expression of epidermicin NI01, a novel unmodified bacteriocin produced by Staphylococcus epidermidis that displays potent activity against Staphylococci.

Authors:  Stephanie Sandiford; Mathew Upton
Journal:  Antimicrob Agents Chemother       Date:  2011-12-12       Impact factor: 5.191

Review 8.  Imipenem resistance of Pseudomonas in pneumonia: a systematic literature review.

Authors:  Marya D Zilberberg; Joyce Chen; Samir H Mody; Andrew M Ramsey; Andrew F Shorr
Journal:  BMC Pulm Med       Date:  2010-08-26       Impact factor: 3.317

9.  Desmethyl macrolides: synthesis and evaluation of 4-desmethyl telithromycin.

Authors:  Ian Glassford; Miseon Lee; Bharat Wagh; Venkata Velvadapu; Tapas Paul; Gary Sandelin; Charles DeBrosse; Dorota Klepacki; Meagan C Small; Alexander D MacKerell; Rodrigo B Andrade
Journal:  ACS Med Chem Lett       Date:  2014-07-16       Impact factor: 4.345

10.  Synthesis, SAR and antibacterial activity of hybrid chloro, dichloro-phenylthiazolyl-s-triazines.

Authors:  Prashant Gahtori; Surajit Kumar Ghosh; Brijesh Singh; Udaya Pratap Singh; Hans Raj Bhat; Archana Uppal
Journal:  Saudi Pharm J       Date:  2011-05-17       Impact factor: 4.330
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