| Literature DB >> 17157020 |
Gaëlle Deglane1, François Morvan, Françoise Debart, Jean-Jacques Vasseur.
Abstract
Incorporation of 5-propynylamino and 5-propynyl alpha-2'-deoxyuridine into alpha-oligonucleotides (alpha-ON) allows high-affinity targeting of complementary DNA for alpha-ON with anionic and neutral backbone but not for cationic alpha-ON, revealing clues on the role of the amino group of the propynylamino on the formation of DNA duplexes.Entities:
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Year: 2006 PMID： 17157020 DOI： 10.1016/j.bmcl.2006.11.052
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823