Literature DB >> 1715696

2,3,7,8-Tetrachlorodibenzo-P-dioxin as a possible activator of HIV infection.

A G Pokrovsky1, A I Cherykh, O N Yastrebova, I B Tsyrlov.   

Abstract

The effects of 10-150 nM 2,3,7,8-TCDD on the HIV infection in the various lymphoid cell cultures have been studied. The level of reproduction of HIV was examined by determination of virus antigen as well as by measurement of reverse trascriptase activity. 2,3,7,8-TCDD does not exert any toxic influence in this concentration on the MT-4 cells and causes the induction of cytochrome P-450-containing monooxygenase. Furthermore, in MT-4 cell culture infected by HIV-1 virus an increase of virus production after a treatment of cells with 2,3,7,8-TCDD has been revealed.

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Year:  1991        PMID： 1715696     DOI： 10.1016/0006-291x(91)91331-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  5 in total

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Authors:  David N Feldman; Joseph G Feldman; Ruth Greenblatt; Kathryn Anastos; Leigh Pearce; Mardge Cohen; Stephen Gange; Suzanne Leanza; Robbie Burk
Journal:  AIDS Educ Prev       Date:  2009-06

2.  Association of high viral load and abnormal liver function with high aflatoxin B1-albumin adduct levels in HIV-positive Ghanaians: preliminary observations.

Authors:  P E Jolly; F M Shuaib; Y Jiang; P Preko; J Baidoo; J K Stiles; J-S Wang; T D Phillips; J H Williams
Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess       Date:  2011-07-12

3.  2,3,7,8-Tetrachlorodibenzo-p-dioxin influences bovine herpesvirus 1 replication through upregulation of SIRT3 and cytoskeletal reorganization.

Authors:  Filomena Fiorito; Valentina Iovane; Annarosaria Marullo; Anna Costagliola; Giovanna Elvira Granato; Luisa De Martino
Journal:  Vet Res Commun       Date:  2017-10-28       Impact factor: 2.459

4.  Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation.

Authors:  Yan-Heng Zhou; Li Sun; Jun Chen; Wei-Wei Sun; Li Ma; Yang Han; Xia Jin; Qing-Xia Zhao; Taisheng Li; Hongzhou Lu; Xiu Qiu; Jian-Hua Wang
Journal:  mBio       Date:  2019-12-17       Impact factor: 7.867

5.  Dioxin activates HIV-1 gene expression by an oxidative stress pathway requiring a functional cytochrome P450 CYP1A1 enzyme.

Authors:  Y Yao; A Hoffer; C Y Chang; A Puga
Journal:  Environ Health Perspect       Date:  1995-04       Impact factor: 9.031
  5 in total

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