| Literature DB >> 17156897 |
Dane M Springer1, Amy Bunker, Bing-Yu Luh, Margaret E Sorenson, Jason T Goodrich, Joanne J Bronson, Kenneth DenBleyker, Thomas J Dougherty, Joan Fung-Tomc.
Abstract
Ring-cleaved pleuromutilin derivatives comprised of a [5.3.1] bicyclic core structure have been synthesized and evaluated in vitro as antibacterial agents. Four of the compounds described were found to have MICs<or=4 microg/mL against marker strains of Streptococcus pneumoniae and Staphylococcus aureus.Entities:
Mesh：
Substances：
Year: 2006 PMID： 17156897 DOI： 10.1016/j.ejmech.2006.07.018
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514