Literature DB >> 17156891

Mutation of epidermal growth factor receptor gene in adenosquamous carcinoma of the lung.

Hidefumi Sasaki, Katsuhiko Endo, Haruhiro Yukiue, Yoshihiro Kobayashi, Motoki Yano, Yoshitaka Fujii.   

Abstract

We have investigated 26 adenosquamous lung cancer tissues and found that four EGFR mutations were mainly in female and non-smoker lung cancer. However, EGFR mutation at kinase domain was exclusive with K-ras mutation. However, smoking and gender status could affect the occurrence of EGFR mutation. There was no difference in EGFR mutation status if analysis was performed in never smoker female subgroup.

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Year:  2006        PMID: 17156891     DOI: 10.1016/j.lungcan.2006.09.003

Source DB:  PubMed          Journal:  Lung Cancer        ISSN: 0169-5002            Impact factor:   5.705


  15 in total

1.  Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations.

Authors:  Natasha Rekhtman; Paul K Paik; Maria E Arcila; Laura J Tafe; Geoffrey R Oxnard; Andre L Moreira; William D Travis; Maureen F Zakowski; Mark G Kris; Marc Ladanyi
Journal:  Clin Cancer Res       Date:  2012-01-06       Impact factor: 12.531

2.  Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR.

Authors:  Marie Brevet; Maria Arcila; Marc Ladanyi
Journal:  J Mol Diagn       Date:  2010-01-21       Impact factor: 5.568

3.  Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.

Authors:  Quanri Jin; David G Menter; Li Mao; Waun Ki Hong; Ho-Young Lee
Journal:  Carcinogenesis       Date:  2008-07-16       Impact factor: 4.944

4.  Adenosquamous cell lung cancer successfully treated with gefitinib: A case report.

Authors:  Koichi Kurishima; Gen Ohara; Katsunori Kagohashi; Hiroko Watanabe; Norio Takayashiki; Atsushi Ishibashi; Hiroaki Satoh
Journal:  Mol Clin Oncol       Date:  2013-12-09

5.  Clinical characteristics and prognosis of patients with lung adenosquamous carcinoma after surgical resection: results from two institutes.

Authors:  Lewei Zhu; Long Jiang; Jie Yang; Weiquan Gu; Jianxing He
Journal:  J Thorac Dis       Date:  2018-04       Impact factor: 2.895

6.  Intratumor Heterogeneity of ALK-Rearrangements and Homogeneity of EGFR-Mutations in Mixed Lung Adenocarcinoma.

Authors:  Federica Zito Marino; Federica Zito Marino; Giuseppina Liguori; Gabriella Aquino; Elvira La Mantia; Silvano Bosari; Stefano Ferrero; Lorenzo Rosso; Gabriella Gaudioso; Nicla De Rosa; Marianna Scrima; Nicola Martucci; Antonello La Rocca; Nicola Normanno; Alessandro Morabito; Gaetano Rocco; Gerardo Botti; Renato Franco
Journal:  PLoS One       Date:  2015-09-30       Impact factor: 3.240

7.  EGFR mutations in surgically resected fresh specimens from 697 consecutive Chinese patients with non-small cell lung cancer and their relationships with clinical features.

Authors:  Yuanyang Lai; Zhipei Zhang; Jianzhong Li; Dong Sun; Yong'an Zhou; Tao Jiang; Yong Han; Lijun Huang; Yifang Zhu; Xiaofei Li; Xiaolong Yan
Journal:  Int J Mol Sci       Date:  2013-12-17       Impact factor: 5.923

8.  Screening for major driver oncogene alterations in adenosquamous lung carcinoma using PCR coupled with next-generation and Sanger sequencing methods.

Authors:  Xiaohua Shi; Huanwen Wu; Junliang Lu; Huanli Duan; Xuguang Liu; Zhiyong Liang
Journal:  Sci Rep       Date:  2016-02-29       Impact factor: 4.379

9.  Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?

Authors:  Erik Vassella; Stephanie Langsch; Matthias S Dettmer; Cornelia Schlup; Maja Neuenschwander; Milo Frattini; Mathias Gugger; Stephan C Schäfer
Journal:  Oncotarget       Date:  2015-09-15

10.  Clinicopathological characteristics and survival outcomes in adenosquamous carcinoma of the lung: a population-based study from the SEER database.

Authors:  Jian Wang; Bi Lian; Ling Ye; Jie Hu; Yuanlin Song
Journal:  Oncotarget       Date:  2017-12-21
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