PURPOSE: To exploit diffusion imaging tractography to produce a two-dimensional (xy) probabilistic population map of the cortical connections within the human internal capsule (IC). MATERIALS AND METHODS: Diffusion tensor imaging (DTI) was carried out on 11 healthy volunteers. We parceled an axial section of the IC according to its connections to the prefrontal, premotor, primary motor, primary somatosensory, posterior parietal, and occipital cortices using our locally developed probabilistic algorithm. RESULTS: A consistent topographical organization was generated that was consistent with our anatomical knowledge of the IC. In addition, our study shows that in humans the anterior half of the IC is occupied by the prefrontal cortex. CONCLUSION: This map may be of clinical use for correlating neurological deficit with hemispheric lesions, particularly those that affect sensorimotor function.
PURPOSE: To exploit diffusion imaging tractography to produce a two-dimensional (xy) probabilistic population map of the cortical connections within the human internal capsule (IC). MATERIALS AND METHODS: Diffusion tensor imaging (DTI) was carried out on 11 healthy volunteers. We parceled an axial section of the IC according to its connections to the prefrontal, premotor, primary motor, primary somatosensory, posterior parietal, and occipital cortices using our locally developed probabilistic algorithm. RESULTS: A consistent topographical organization was generated that was consistent with our anatomical knowledge of the IC. In addition, our study shows that in humans the anterior half of the IC is occupied by the prefrontal cortex. CONCLUSION: This map may be of clinical use for correlating neurological deficit with hemispheric lesions, particularly those that affect sensorimotor function.
Authors: T E J Behrens; H Johansen-Berg; M W Woolrich; S M Smith; C A M Wheeler-Kingshott; P A Boulby; G J Barker; E L Sillery; K Sheehan; O Ciccarelli; A J Thompson; J M Brady; P M Matthews Journal: Nat Neurosci Date: 2003-07 Impact factor: 24.884
Authors: A Kumar; C Juhasz; E Asano; S K Sundaram; M I Makki; D C Chugani; H T Chugani Journal: AJNR Am J Neuroradiol Date: 2009-08-06 Impact factor: 3.825
Authors: Jungsu S Oh; Marek Kubicki; Gudrun Rosenberger; Sylvain Bouix; James J Levitt; Robert W McCarley; Carl-Fredrik Westin; Martha E Shenton Journal: Hum Brain Mapp Date: 2009-11 Impact factor: 5.038
Authors: Lisa H Lu; Xiaohong Joe Zhou; Jacklynn Fitzgerald; Sarah K Keedy; James L Reilly; Alessandra M Passarotti; John A Sweeney; Mani Pavuluri Journal: Bipolar Disord Date: 2012-08-13 Impact factor: 6.744