Literature DB >> 1715167

The dominant self and the cryptic self: shaping the autoreactive T-cell repertoire.

G Gammon1, E E Sercarz, G Benichou.   

Abstract

Deletion of autoreactive T cells during the induction of self tolerance has been directly demonstrated. However, it is still relatively easy to detect self reactivity in normal healthy animals. In this article, Guy Gammon, Eli Sercarz and Gilles Benichou speculate on which T cells may escape tolerance induction and discuss how these cells could subsequently be involved in autoimmunity.

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Year:  1991        PMID： 1715167     DOI： 10.1016/0167-5699(91)90052-U

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  21 in total

1.  Acquisition of immune function during the development of the Langerhans cell network in neonatal mice.

Authors:  A L Dewar; K V Doherty; G M Woods; A B Lyons; H K Muller
Journal:  Immunology       Date:  2001-05       Impact factor: 7.397

2.  Suppression of murine collagen-induced arthritis by nasal administration of collagen.

Authors:  L K Myers; J M Seyer; J M Stuart; A H Kang
Journal:  Immunology       Date:  1997-02       Impact factor: 7.397

3.  Antigen-specific T cell recognition of affinity-purified and recombinant thyroid peroxidase in autoimmune thyroid disease.

Authors:  D L Ewins; P S Barnett; S Ratanachaiyavong; C Sharrock; J Lanchbury; A M McGregor; J P Banga
Journal:  Clin Exp Immunol       Date:  1992-10       Impact factor: 4.330

Review 4.  Self determinant selection and acquisition of the autoimmune T cell repertoire.

Authors:  G Benichou; R C Tam; P I Orr; M R Garovoy; E V Fedoseyeva
Journal:  Immunol Res       Date:  1996       Impact factor: 2.829

5.  Viewing Autoimmune Pathogenesis from the Perspective of Antigen Processing and Determinant Hierarchy.

Authors:  Kamal D Moudgil
Journal:  Crit Rev Immunol       Date:  2020       Impact factor: 2.214

Review 6.  Cellular basis of T-cell autoreactivity in autoimmune diseases.

Authors:  C Carnaud; J F Bach
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

7.  T cell reactivity to proteinase 3 and myeloperoxidase in patients with Wegener's granulomatosis (WG).

Authors:  E Brouwer; C A Stegeman; M G Huitema; P C Limburg; C G Kallenberg
Journal:  Clin Exp Immunol       Date:  1994-12       Impact factor: 4.330

8.  Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro.

Authors:  C A Akdis; M Akdis; T Blesken; D Wymann; S S Alkan; U Müller; K Blaser
Journal:  J Clin Invest       Date:  1996-10-01       Impact factor: 14.808

9.  Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants.

Authors:  R Cibotti; J M Kanellopoulos; J P Cabaniols; O Halle-Panenko; K Kosmatopoulos; E Sercarz; P Kourilsky
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

10.  A synthetic peptide from the third hypervariable region of major histocompatibility complex class II beta chain as a vaccine for treatment of experimental autoimmune encephalomyelitis.

Authors:  D J Topham; B Nag; S Arimilli; S Sriram
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-16       Impact factor: 11.205
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