| Literature DB >> 17150789 |
Abstract
We herein report a convenient synthesis of 3',5'-cyclic diguanylic acid (cdiGMP) through the modified H-phosphonate chemistry. The 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl (Cpep) group was used as protecting group for the 2'-hydroxy functions of ribonucleosides. Homogeneous cdiGMP was obtained after removal of the protecting groups.Entities:
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Year: 2006 PMID： 17150789 DOI： 10.1093/nass/nrl003
Source DB: PubMed Journal: Nucleic Acids Symp Ser (Oxf) ISSN： 0261-3166