| Literature DB >> 17150513 |
Toshiyuki Takiya1, Yasuhiro Seto, Hideyo Yasuda, Tohru Suzuki, Keiichi Kawai.
Abstract
To predict the Tm value of PNA/DNA duplex, we performed to determine the melting temperature of several PNA oligomers. For Tm calculation model building, we searched the correlativity of measured Tm value and each base contents of PNA oligomer. Here, We propose a novel formula for thermal stability (Tm) prediction of PNA/DNA duplexes.Mesh:
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Year: 2004 PMID: 17150513 DOI: 10.1093/nass/48.1.131
Source DB: PubMed Journal: Nucleic Acids Symp Ser (Oxf) ISSN: 0261-3166