Literature DB >> 17150513

An empirical approach for thermal stability (Tm) prediction of PNA/DNA duplexes.

Toshiyuki Takiya1, Yasuhiro Seto, Hideyo Yasuda, Tohru Suzuki, Keiichi Kawai.   

Abstract

To predict the Tm value of PNA/DNA duplex, we performed to determine the melting temperature of several PNA oligomers. For Tm calculation model building, we searched the correlativity of measured Tm value and each base contents of PNA oligomer. Here, We propose a novel formula for thermal stability (Tm) prediction of PNA/DNA duplexes.

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Year:  2004        PMID: 17150513     DOI: 10.1093/nass/48.1.131

Source DB:  PubMed          Journal:  Nucleic Acids Symp Ser (Oxf)        ISSN: 0261-3166


  1 in total

1.  Development of peptide nucleic acid probes for detection of the HER2 oncogene.

Authors:  Belhu Metaferia; Jun S Wei; Young K Song; Jennifer Evangelista; Konrad Aschenbach; Peter Johansson; Xinyu Wen; Qingrong Chen; Albert Lee; Heidi Hempel; Jinesh S Gheeya; Stephanie Getty; Romel Gomez; Javed Khan
Journal:  PLoS One       Date:  2013-04-10       Impact factor: 3.240

  1 in total

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