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Literature DB >> 17149457

Ondansetron treatment in a child presenting with chronic intractable pruritus.

Abstract

The case of a seven-year-old boy with chronic pruritus secondary to a giant congenital melanocytic nevus is presented. The pruritus did not respond to conventional antipruritic drug treatment, but responded to ondansetron, a selective antagonist of 5-hydroxytryptamine type 3 receptors.

Entities: Chemical Disease Species

Mesh：

Substances：
Antipruritics
Ondansetron

Year: 2006 PMID： 17149457 PMCID： PMC2673141 DOI： 10.1155/2006/873870

Source DB: PubMed Journal: Pain Res Manag ISSN： 1203-6765 Impact factor: 3.037

26 in total

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Authors: R J Gralla; D Osoba; M G Kris; P Kirkbride; P J Hesketh; L W Chinnery; R Clark-Snow; D P Gill; S Groshen; S Grunberg; J M Koeller; G R Morrow; E A Perez; J H Silber; D G Pfister
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Authors:
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Authors: M Schmelz; R Schmidt; A Bickel; H O Handwerker; H E Torebjörk
Journal: J Neurosci Date: 1997-10-15 Impact factor: 6.167

4. Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients.

Authors: E V Balaskas; G I Bamihas; M Karamouzis; G Voyiatzis; A Tourkantonis
Journal: Nephron Date: 1998 Impact factor: 2.847

5. Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child.

Authors: Jing Feng; Aisha Sethi; Miguel Reyes-Múgica; Richard Antaya
Journal: J Am Acad Dermatol Date: 2005-08 Impact factor: 11.527

Ondansetron treatment in a child presenting with chronic intractable pruritus.

1. Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical Oncology.

Review 2. ASHP Therapeutic Guidelines on the Pharmacologic Management of Nausea and Vomiting in Adult and Pediatric Patients Receiving Chemotherapy or Radiation Therapy or Undergoing Surgery.

3. Specific C-receptors for itch in human skin.

4. Histamine and serotonin in uremic pruritus: effect of ondansetron in CAPD-pruritic patients.

5. Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child.

6. Ondansetron for paediatric uraemic pruritus: a case report.

7. Intrathecal fentanyl-induced pruritus during labour: the effect of prophylactic ondansetron.

8. Prophylactic ondansetron does not reduce the incidence of itching induced by intrathecal sufentanil.

9. Ondansetron is effective to treat spinal or epidural morphine-induced pruritus.

Review 10. Neurophysiology of pruritus: cutaneous elicitation of itch.

1. Neurocutaneous melanocytosis (melanosis).

2. Ondansetron to treat pruritus due to cholestatic jaundice.

3. Medication Repurposing in Pediatric Patients: Teaching Old Drugs New Tricks.